The document discusses mitochondrial respiratory complexes and respirasomes. It notes that the complexes assemble into larger structures called respirasomes, which are necessary for stable respiratory function. There are four main complexes involved in oxidative phosphorylation. The complexes work together to establish a proton gradient used by ATP synthase to generate ATP. Dysfunction can lead to diseases. Recent cryo-EM studies have provided structural information on respiratory supercomplexes in various organisms, revealing details of protein interactions and organization principles.