Mechanisms, imaging, and therapy in stroke recovery

C Xing, K Hayakawa, EH Lo - Translational Stroke Research, 2017 - Springer
Although the majority of phase II/III clinical trials of neuroprotective drugs have failed, recent
clinical trials of endovascular recanalization using mechanical thrombectomy were proved …

Efficacy and safety of naoshuantong capsule in the treatment of ischemic stroke: a meta-analysis

H Zhang, Y Xing, J Chang, L Wang, N An… - Frontiers in …, 2019 - frontiersin.org
Background: Ischemic stroke (IS) is a leading cause of death and long-term disability
worldwide. The NaoShuanTong capsule (NSTC), a traditional Chinese patent medicine, has …

Endovascular equipoise shift in a phase III randomized clinical trial of sonothrombolysis for acute ischemic stroke

AV Alexandrov, G Tsivgoulis… - Therapeutic …, 2019 - journals.sagepub.com
Background: Results of our recently published phase III randomized clinical trial of
ultrasound-enhanced thrombolysis (sonothrombolysis) using an operator-independent, high …

Reperfusion injury in acute ischemic stroke: Tackling the irony of revascularization

S Soldozy, C Dalzell, A Skaff, Y Ali, P Norat… - Clinical Neurology and …, 2023 - Elsevier
Reperfusion injury is an unfortunate consequence of restoring blood flow to tissue after a
period of ischemia. This phenomenon can occur in any organ, although it has been best …

Development of a routinely applicable imaging protocol for fast and precise middle cerebral artery occlusion assessment and perfusion deficit measure in an ovine …

AM Herrmann, GFM Cattaneo, SA Eiden… - Frontiers in …, 2019 - frontiersin.org
Temporary middle cerebral artery occlusion (MCAO) in sheep allows modeling of acute
large vessel occlusion stroke and subsequent vessel recanalization. However, rapid and …

Clinical outcome prediction after thrombectomy of proximal middle cerebral artery occlusions by the appearance of lenticulostriate arteries on magnetic resonance …

J Kaesmacher, K Kreiser, NW Manning… - Journal of Cerebral …, 2018 - journals.sagepub.com
Post-ischemic vasodynamic changes in infarcted brain parenchyma are common and range
from hypo-to hyperperfusion. In the present study, appearance of the lenticulostriate arteries …

Correcting the trajectory of stroke therapeutic research

KR Pennypacker, G Bix, JF Fraser - Translational stroke research, 2017 - Springer
One of the most vital issues in stroke research is the paucity of animal studies that have
translated into treatments for human stroke patients. The August and October issues of this …

Transcervical access via direct neck exposure for neurointerventional procedures in the hybrid angiosuite

JY Lee, JH Park, HJ Jeon, DY Yoon, SW Park, BM Cho - Neuroradiology, 2018 - Springer
Purpose A complicated course of the femoral route for neurointervention can prevent
approaching the target. Thus, we determined whether transcervical access in the hybrid …

Infusion warm during selective hypothermia in acute ischemic stroke

TL Merrill, BF Smith, JE Mitchell, DR Merrill… - Brain …, 2019 - journals.lww.com
MATERIALS AND METHODS: We explored various warming effects that can reduce the
effectiveness or potency of selective hypothermia during AIS under conditions similar to …

Stroke cytoprotection: can repeating history with new expectations really be the path to success in stroke research?

PA Lapchak, VV Uteshev - Translational stroke research, 2017 - Springer
Dear Editor: It appears that a key guideline directly applicable to today's stroke research has
been formulated years ago by Albert Einstein:“In order to succeed, your desire for success …