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"Improving reperfusion therapies in the era of mechanical thrombectomy" - new citations

Sample results2 results in the last year.

A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke

PD Lyden, MA Diniz, F Bosetti, J Lamb, KA Nagarkatti… - Science translational …, 2023
Human diseases may be modeled in animals to allow preclinical assessment of
putative new clinical interventions. Recent, highly publicized failures of large clinical
trials called into question the rigor, design, and value of preclinical assessment. We …

Reperfusion injury in acute ischemic stroke: Tackling the irony of revascularization

S Soldozy, C Dalzell, A Skaff, Y Ali, P Norat… - Clinical Neurology and …, 2023
Reperfusion injury is an unfortunate consequence of restoring blood flow to tissue
after a period of ischemia. This phenomenon can occur in any organ, although it has
been best studied in cardiac cells. Based on cardiovascular studies, neuroprotective …