Cholinergic synapses are ubiquitous in the human central nervous system. Their high
density in the thalamus, striatum, limbic system, and neocortex suggest that cholinergic …

Aim The aim was to investigate associations between drugs with anticholinergic effects
(DACEs) and cognitive impairment, falls and all‐cause mortality in older adults. Methods A …

The 2015 American Geriatrics Society (AGS) Beers Criteria are presented. Like the 2012
AGS Beers Criteria, they include lists of potentially inappropriate medications to be avoided …

Importance Anticholinergic medicines have short-term cognitive adverse effects, but it is
uncertain whether long-term use of these drugs is associated with an increased risk of …

Myopia is a global problem that is increasing at an epidemic rate in the world. Although the
refractive error can be corrected easily, myopes, particularly those with high myopia, are …

Lower urinary tract dysfunction is a common sequel of neurological disease resulting in
symptoms that significantly impacts quality of life. The site of the neurological lesion and its …

Background/rationale Long‐term treatment with anticholinergic agents may increase the risk
of cognitive impairment or dementia. This systematic literature review and meta‐analysis …

Objectives To investigate the association between anticholinergic drug burden (ADB),
measured with anticholinergic drug scales, and delirium and delirium severity. Design …

Elderly surgical patients frequently experience postoperative delirium (POD) and the
subsequent development of postoperative cognitive dysfunction (POCD). Clinical features …

Abstract Purpose Although Alzheimer disease and related dementias (ADRDs) have long
been considered nonpreventable and even an inevitable consequence of aging, recent …