Interventions for reducing anticholinergic medication burden in older adults—a systematic review and meta-analysis
E Braithwaite, OM Todd, A Atkin, R Hulatt… - Age and …, 2023 - academic.oup.com
Introduction Anticholinergic medications block the neurotransmitter acetylcholine in the brain
and peripheral nervous system. Many medications have anticholinergic properties, and the …
and peripheral nervous system. Many medications have anticholinergic properties, and the …
The prognostic utility of anticholinergic burden scales: an integrative review and gap analysis
HU Michael, O Enechukwu, MJ Brouillette, R Tamblyn… - Drugs & Aging, 2023 - Springer
Background Anticholinergic drugs are commonly prescribed, especially to older adults.
Anticholinergic burden scales (ABS) have been used to evaluate the cumulative effects of …
Anticholinergic burden scales (ABS) have been used to evaluate the cumulative effects of …
Delirium‐associated medication in people at risk: A systematic update review, meta‐analyses, and GRADE‐profiles
M Reisinger, EZ Reininghaus, JD Biasi… - Acta Psychiatrica …, 2023 - Wiley Online Library
Background Drug‐associated delirium is a common but potentially preventable
neuropsychiatric syndrome associated with detrimental outcomes. Empirical evidence for …
neuropsychiatric syndrome associated with detrimental outcomes. Empirical evidence for …
Association of anticholinergic drug exposure with the risk of dementia among older adults in Japan: The LIFE Study
Y Okita, T Kitamura, S Komukai, L Zha… - … Journal of Geriatric …, 2023 - Wiley Online Library
Objectives Several studies have investigated that anticholinergic drugs cause cognitive
impairment. However, the risk of dementia associated with anticholinergics has not been …
impairment. However, the risk of dementia associated with anticholinergics has not been …
Geriatricians, general internists, and potentially inappropriate medications for a national sample of older adults
JL Vandergrift, W Weng, B Leff… - Journal of the American …, 2024 - Wiley Online Library
Background Older adults are often prescribed medications that are potentially dangerous
and geriatricians have specialized training in treating polypharmacy that may benefit these …
and geriatricians have specialized training in treating polypharmacy that may benefit these …
Adherence to overactive bladder syndrome treatments recent developments and future perspectives
D Robinson, M O'Kane, L Cardozo - International Journal of …, 2023 - Taylor & Francis
Overactive bladder (OAB) is a common and distressing condition which is known to have a
significant effect on Health-Related Quality of Life (HRQoL). Whilst all patients complaining …
significant effect on Health-Related Quality of Life (HRQoL). Whilst all patients complaining …
Frequency and clinical impact of anticholinergic burden in older patients: comparing older patients with and without chronic kidney disease
Aim This study aimed to determine the frequency and impact of anticholinergic burden in
older adults with chronic kidney disease (CKD) and compare the results to older adults …
older adults with chronic kidney disease (CKD) and compare the results to older adults …
Factors influencing central nervous system medication deprescribing and behavior change in hospitalized older adults
Background Central nervous system (CNS) medications are linked to higher morbidity and
mortality in older adults. Hospitalization allows for deprescribing opportunities. This …
mortality in older adults. Hospitalization allows for deprescribing opportunities. This …
A pilot study investigating cognitive impairment associated with opioid overdose
Background In 2021, while overdose (OD) deaths were at the highest in recorded history, it
is estimated that> 80% of ODs do not result in a fatality. While several case studies have …
is estimated that> 80% of ODs do not result in a fatality. While several case studies have …
Longitudinal post-shunt outcomes in idiopathic normal pressure hydrocephalus with and without comorbid Alzheimer's disease
D Gold, C Wisialowski, I Piryatinsky… - Journal of the …, 2023 - cambridge.org
Objective: Alzheimer's disease (AD) is highly comorbid with idiopathic normal pressure
hydrocephalus (iNPH) and may diminish the benefits of shunting; however, findings in this …
hydrocephalus (iNPH) and may diminish the benefits of shunting; however, findings in this …