Factors influencing central nervous system medication deprescribing and behavior change in hospitalized older adults

JM Pavon, AD Zhang, LJ Fish… - Journal of the …, 2024 - Wiley Online Library
Background Central nervous system (CNS) medications are linked to higher morbidity and
mortality in older adults. Hospitalization allows for deprescribing opportunities. This …

Geriatricians, general internists, and potentially inappropriate medications for a national sample of older adults

JL Vandergrift, W Weng, B Leff… - Journal of the American …, 2024 - Wiley Online Library
Background Older adults are often prescribed medications that are potentially dangerous
and geriatricians have specialized training in treating polypharmacy that may benefit these …

Association between Comorbidity Indices and Functional Autonomy in Individuals with Cognitive Impairment: A Systematic Review

MN Temedda, A Garnier-Crussard, C Mouchoux… - The Journal of …, 2024 - Springer
This systematic review aimed to examine whether higher comorbidity burden, as assessed
by comorbidity indices, was associated with a functional autonomy decline in individuals …

Associations between multimorbidity and neuropathology in dementia: consideration of functional cognitive disorders, psychiatric illness and dementia mimics

CA Hamilton, FE Matthews, J Attems… - The British Journal of …, 2024 - cambridge.org
BackgroundMultimorbidity, the presence of two or more health conditions, has been
identified as a possible risk factor for clinical dementia. It is unclear whether this is due to …

Prevalence and Appropriateness of Polypharmacy in Older Adults with Inflammatory Bowel Diseases

B Kochar, A Rusher, E Araka, R Glasser, J Lai… - Digestive Diseases and …, 2024 - Springer
Background Despite the growing prevalence of older adults with inflammatory bowel
diseases (IBD), polypharmacy, an important geriatric construct, is poorly understood. We …

A Mediation Analysis Examining High Risk, Anticholinergic Medication Use, Delirium, and Dementia After Major Surgery

S Mohanty, H Lindroth, L Timsina, E Holler… - Journal of Surgical …, 2024 - Elsevier
Introduction Anticholinergic medications are known to cause adverse cognitive effects in
community-dwelling older adults and medical inpatients, including dementia. The …

What is the best first choice oral drug therapy for OAB?

A Sahai, D Robinson, P Abrams… - Neurourology and …, 2024 - Wiley Online Library
Aims The management of overactive bladder (OAB) involves lifestyle changes and
conservative measures in the first instance with the use of liquid/dietary advice, weight loss …

Features of Polypharmacy in Dutch Older Outpatients with Personality Disorders: A Cross-Sectional Study

J EM Schulkens, S PJ van Alphen… - European Journal of …, 2024 - real.mtak.hu
Introduction: Pharmacotherapy in older adults with personality disorders (PDs) can be even
more complicated compared to younger adults, because older adults stand at risk for …

Voiding Problems and Urinary Incontinence in the Geriatric Patient

LA Wright, P Hamilton, GA Kuchel, PP Smith - Geriatric Medicine: A Person …, 2024 - Springer
Urinary incontinence (UI) is defined as the involuntary loss of urine. It is common, under-
reported, and morbid. More so in older adults than in younger adults, urinary incontinence …

[HTML][HTML] Long term safety outcomes and continuation rates of repeated Intravesical Botulinum Toxin A injections for Detrusor Overactivity: 16 year's experience of a …

R Mohamed-Ahmed, C Tomlinson, A Taithongchai… - Continence, 2024 - Elsevier
Introduction: Overactive bladder (OAB) affects 27% of women in the UK with an adverse
impact on quality of life. Medical treatment with anticholinergics has a high discontinuation …