Recent advances on the role of brain-derived neurotrophic factor (BDNF) in neurodegenerative diseases

KF Azman, R Zakaria - International journal of molecular sciences, 2022 - mdpi.com
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …

[HTML][HTML] Kaempferol, a potential neuroprotective agent in neurodegenerative diseases: From chemistry to medicine

S Jin, L Zhang, L Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Neurodegenerative diseases (NDDs) encompass a range of conditions that involve
progressive deterioration and dysfunction of the nervous system. Some of the common …

[HTML][HTML] Intranasal delivery of BDNF-loaded small extracellular vesicles for cerebral ischemia therapy

X Zhou, X Deng, M Liu, M He, W Long, Z Xu… - Journal of Controlled …, 2023 - Elsevier
Mesenchymal stem cells (MSCs) have shown promise for the therapy of cerebral ischemia in
animal studies and clinical trials, yet their clinical application still faces many challenges …

Recent advances on the molecular mechanisms of exercise-induced improvements of cognitive dysfunction

Y Lu, FQ Bu, F Wang, L Liu, S Zhang, G Wang… - Translational …, 2023 - Springer
Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways

H Kang, W Zhang, J Jing, D Huang, L Zhang… - Journal of Hazardous …, 2023 - Elsevier
The production of plastic is still increasing globally, which has led to an increasing number
of plastic particles in the environment. Nanoplastics (NPs) can penetrate the blood-brain …

The role of brain derived neurotrophic factor in central nervous system

Y Li, F Li, D Qin, H Chen, J Wang, J Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …

Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis

A Wu, J Zhang - Journal of Neuroinflammation, 2023 - Springer
As one of most common and severe mental disorders, major depressive disorder (MDD)
significantly increases the risks of premature death and other medical conditions for patients …

Possible antidepressant mechanisms of omega-3 polyunsaturated fatty acids acting on the central nervous system

L Zhou, JY Xiong, YQ Chai, L Huang, ZY Tang… - Frontiers in …, 2022 - frontiersin.org
Omega-3 polyunsaturated fatty acids (PUFAs) can play important roles in maintaining
mental health and resistance to stress, and omega-3 PUFAs supplementation can display …

Benefits from repetitive transcranial magnetic stimulation in post-stroke rehabilitation

M Starosta, N Cichoń, J Saluk-Bijak, E Miller - Journal of clinical medicine, 2022 - mdpi.com
Stroke is an acute neurovascular central nervous system (CNS) injury and one of the main
causes of long-term disability and mortality. Post-stroke rehabilitation as part of recovery is …

Selenium ameliorates mercuric chloride-induced brain damage through activating BDNF/TrKB/PI3K/AKT and inhibiting NF-κB signaling pathways

LX Li, JH Chu, XW Chen, PC Gao, ZY Wang… - Journal of Inorganic …, 2022 - Elsevier
Abstract Mercuric chloride (HgCl 2), a heavy metal compound, causes neurotoxicity of
animals and humans. Selenium (Se) antagonizes heavy metal-induced organ damage with …