1) Nearly 1 in 100 people aged 15-64 in Great Britain is considered a high-risk drug user, defined as injecting drugs or regular long-term use of opioids, cocaine, and/or amphetamines.
2) In 2013-14, there were 47,900 child assessments where alcohol or other drugs were a factor, and 435 children in foster care ran away due to substance misuse.
3) Prisoners have high rates of drug use and mental health problems, and older prisoners are more likely to have used Class A drugs before entering custody.
This document contains multiple figures and charts related to alcohol and drug use in the UK. It shows that:
1) Between 2013-2014, 584 online drug shops were identified across multiple European countries, with 18% (106 shops) no longer active by May 2014.
2) Data from 26 UK police forces showed that 10% of sexual offenses were alcohol-related.
3) A study found reductions in criminal offending after treatment for alcohol use disorder, with less offending associated with completing treatment and pharmacological therapy.
4) The document presents statistics on drug prices, purity, seizures and other measures related to alcohol and drug use in the UK.
Interesting things about alcohol and other drugs - May 2017Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - Feb 2017Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - August 2017Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - June 2017Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - April 2017Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - March 2017Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - Dec 2016Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - November 2017Andrew Brown
This document contains multiple summaries and statistics related to alcohol and drug use in the UK:
- The number of adults in community drug and alcohol treatment has fallen slightly in recent years, particularly for alcohol alone. Crack cocaine problems have increased 23%.
- Housing problems fell for most substance users between starting treatment and 6 months later, ranging from 3-5% reductions.
- Non-fatal overdoses have risen among people who inject drugs in England, reaching 19% in 2016. Rates are lower for those currently in treatment.
- Reoffending fell 33% overall for those in community substance misuse treatment, with the greatest reductions for alcohol-only clients in both offenders (59%) and offenses
Interesting things about alcohol and other drugs - July 2017Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - Nov 2016Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - Oct 2016Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
Interesting things about alcohol and other drugs - October 2017Andrew Brown
One in a regular series of slide sets on interesting data about alcohol and other drugs (and the wider issues to do with multiple needs) from a UK perspective.
10 things about drugs you may have missedAndrew Brown
Including: drug related deaths in Scotland, prescriptions for treating substance dependence, new psychoactive substances, numbers of benefits recipients in England with drug and alcohol problems, the number of controlled drugs prescribed by the NHS, e-cigarettes, and the use of stop and search powers for drugs as used by police in England.
Local Alcohol Profiles for England (LAPE) commentary February 2018Public Health England
- The document provides an overview of key findings from the updated Local Alcohol Profiles for England (LAPE) data for 2016/17, including trends in alcohol-related hospital admissions.
- Over 1.1 million hospital admissions in 2016/17 were linked to alcohol on the broad measure. Admissions on the narrow measure fell slightly but the trend is broadly flat.
- Chronic conditions partially caused by alcohol make up the majority of alcohol-related admissions, with cardiovascular diseases being the largest group.
The document discusses rising drug-related deaths in the UK. It notes concerns from the drug and alcohol sector about increasing deaths due to factors like more heroin users leaving services, less outreach work, an aging user population, and higher strength heroin. Some areas reported that increased access to naloxone, which reverses overdoses, prevented deaths. Data showed drug-related deaths rising in some regions from 2013 to 2014. A professional said most deaths were from long-term organ damage in aging opiate users rather than overdoses.
The average Christmas dinner contains as much as 956 calories and 46g of fat.In this presentation, you will see how much weight you gained during Christmas time and what you can do to cut calories during those festive days. ~ Shared by: http://www.familychiropractic.com.sg/
Good Health is Real Wealth at WorkplaceAnkur Tandon
Companies who are aggressively planning out to create a positive work atmosphere are advised to take examples from the major brands who always try to build their work environment employees-friendly.
Read more interesting content, at www.thecareermuse.co.in - We intend to inform and inspire recruiters, job seekers and anyone with an interest in the workplace and HR technology.
Hope you enjoyed reading the Infographic.
Feel free to share your feedback with us at @CareerBuilderIn
This document summarizes a Twitter discussion about healthy and frugal eating during the holidays. Participants shared tips like cooking at home to control calories and portion sizes, buying produce in season, shopping sales and using coupons. Favorite healthy dishes included grilled pork loin and roasted brussel sprouts. When eating out, strategies like splitting meals or taking half home were suggested to avoid overeating. Tracking calories with apps like MyFitnessPal was also discussed.
The Future of Medical Education - Top Trends Likely to Have an Impact on the ...Ogilvy Health
The document summarizes key trends that are likely to impact the healthcare industry in the next decade based on a panel discussion with experts. Three major trends are: 1) Increased accountability and use of real-world data by pharmaceutical companies as patients have more medical information. 2) The rise of the "digitally enabled patient" as wearables and devices give patients and doctors more data to self-monitor health. 3) The impact of hyper-connected learners who will increasingly personalize their medical education online.
Design for Change: Empathy as our Guide: Amy Cueva Keynote at Partners Center...Amy Cueva
This presentation was a part of the "Design for Change" track at the October 29, 2015 Partners Center for Connected Health Symposium. The presentation discusses how Empathy can be our guide as we seek to improve health experiences.
The Spring Festival, also known as the Chines New Year, is the most important Chinese festival celebrated each year. Many traditions have significant influence on people’s life.
Read the infographic “ Chinese New Year - the Spring Festival”.
Whether it's prescription or street drugs, when the demise includes a celebrated face, it attracts consideration regarding evil spirits that neither cash nor notoriety can tame. These 16 stars lost their lives to overdoses, yet their legacy lives on in the collection of work they deserted.
Science of Achievement & Art of Fulfillment | Tony Robbins Tony Robbins
What does it mean to live an extraordinary life? It means living life on your own terms. And to do that, you must master two skills: The science of achievement and the art of fulfillment. Hear Tony explain why success without fulfillment is the ultimate failure.
Your Keys to an Extraordinary Life of Fulfillment:
Health, Time, Wealth, Business, Mind & Spirit, Relationships
For more insights, strategies and tools, visit: http://tonyr.co/1Ol6IJH
Visit Tony Robbins' websites:
https://www.tonyrobbins.com/
http://humanelevation.tonyrobbins.com/
https://moneymasterthegame.com/
Follow Tony Robbins @:
Facebook: https://www.facebook.com/TonyRobbins
Twitter: https://twitter.com/tonyrobbins
LinkedIn: https://www.linkedin.com/in/ajrobbins
Google+: https://plus.google.com/+TonyRobbins
Instagram: https://instagram.com/tonyrobbins/
Tony Robbins is a #1 New York Times best-selling author, entrepreneur, and philanthropist. For more than 37 years, millions of people have enjoyed the warmth, humor and dynamic presentation of Mr. Robbins' corporate and personal development events. As the nation's #1 life and business strategist, he¹s called upon to consult and coach some of the world¹s finest athletes, entertainers, Fortune 500 CEOs, and even presidents of nations.
Having trouble falling asleep? Insomnia is one of the most common side effects of cancer treatment. This presentation provides tips for how you can get some rest without using medication.
10 Easy Ways to Unleash Your Kid's Brain PowerSage HR
Do you know that a baby is born with all the brain cells he needs when he becomes an adult?
Do you know that a baby creates 700 neural connections every second in the first 1,000 days of his life?
A study conducted by Dr. Jim Heckman, a Nobel Laureate in Economics, show that early stimulation of brain function during childhood plays a critical role in a child's social and economic success. Furthermore, the neural pathways and networks that are forged during the first 1,000 days will have lasting impacts on the person's social, emotional and mental capabilities --- very important factors which dictate the kind of lifestyle, job and social interactions he will have in the future.
For parents who want nothing but the best for their children, Dr. Heckman's research show that preschool experiences and early interactions with peers and adults provide the highest return in capital investment. The benefits of which decreases dramatically after school due to aging and several other reasons.
From an economic standpoint, these words ring true. Early childhood stimulation of brain function develops fluid abilities such as memory, reasoning, speed of thought and problem solving prowess. All of which are interrelated and foreshadows high-level brain function which is key to a happy, successful life.
In this Slideshare story deck, CakeHR is proud to present 10 easy, practical ways to develop your kid's brain power. Here you will learn about the importance of play, songs and interactive toys in early childhood brain stimulation. You will also learn that the way your respond to your child's needs and cries will have a direct effect on the development of his cognitive and emotional abilities.
Learn more about CakeHR at > > > cake.hr
Is healthwashing the new greenwashing? Are we placing too much faith in technology? These are just some of the questions that emerged from our conversation around making health a shared value at TEDMED 2015. Check out our blog, "Overheard at TEDMED: Let's Dance," for more details: http://blog.tedmed.com/overheard-at-tedmed/
Whether you’re fooled by a push/pull door or you unexpectedly run into an academic lecturer outside of class, the best advice we can give you? Embrace the awkward! We’ve put together the most common awkward student moments you’re likely to run into during university life and added some handy tips on how to embrace them.
Visit
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Wondering how on earth these celebrities manage to keep the glow of their skin on for years.
Magic or expensive cosmetics?
No, the name of the magic is yoga.
Yoga is the answer to all physical, mental and spiritual development.
1. Bhujangasana (Cobra Pose):
2. Ustrasana (Camel Pose):
3. Matsyasana (Fish Pose):
4. Halasana (Plow Pose):
5. Trikonasana (Triangle pose):
6. Pavanmuktasana (Wind Relieving pose):
7. Breathing Exercise:
Glowing Skin Remedies For Normal Skin Types:
• Mix the juice of half a tomato or orange with two tsp yoghurt. Massage your face with this preparation with upward strokes for a few minutes. Keep on till it dries and then wash off with cold water.• Massage your face using the inner part of a papaya peel. When it dries, wash with cold water.
• Grind half cup cabbage or press out the juice from the resulting pulp. Apply and cleanse it off after it dries. You can do the same thing with a small carrot.• Use the inner part of apple peels to massage your face and wash off with cold water when dry.• Rub an ice cube on your face. Pat dry. This helps to improve blood circulation and brings a natural glow to the skin.
This document summarizes several factors that can lead to interpersonal attraction according to social psychology research: physical appearance/beauty, personality, proximity, and similarity. Studies discussed found that people tend to see attractive, beautiful people as more desirable and competent. Additionally, having a warm, kind, or exciting personality is attractive to others. Proximity, or spending time near others, increases comfort levels and likelihood of attraction. Similarity in characteristics and interests between people also reduces conflicts. Reciprocated liking and gaining the approval of someone who was initially unimpressed can be especially rewarding.
How can cancer patients manage the symptoms of chemobrain? Learn more about this side effect of cancer treatment, which can sometimes cause decreased short-term memory, problems finding words, short attention span, and difficulty concentrating and multitasking.
Interesting things you may have missed - April 2015Andrew Brown
The document summarizes several statistics related to drug use in Scotland and the UK:
- An estimated 46,657 people in Scotland injected drugs with hepatitis C in 2009, with over 27,000 being undiagnosed. Most undiagnosed cases were non-recent drug users aged 35-64.
- In England and Wales in 2014, over 100,000 arrests were for drug offenses, though this was down from the previous year. The majority of stop-and-searches and subsequent arrests involved attempts to find Class A drugs.
- Over 1,300 children in Scotland lost a parent to a drug-related death between 2009-2013. Women who died were more likely to live with and care
10 interesting things about alcohol and other drugs that you might have misse...Andrew Brown
Including - tax revenue from alcohol across Europe, mortality rates for lung cancer, daily doses of OST in Scotland, milligrams of methadone prescribed in Scotland, reasons given for refusing 'place of safety' under the Mental Health Act, calls to the NPIS about drugs, prisoners ability to access drugs and alcohol in England, absconders from prison, re-offending drug offenders in England
Interesting things about alcohol and other drugs that you might have missed -...Andrew Brown
This month includes data on:
Deaths amongst opioid users (esp those which are not overdose related); children in need and care and substance use problems; multiple and complex needs; trends in police recorded drug offences; gang membership, dependency and mental health problems; Seizures of synthetic cannabinoids in prison; public perceptions of the safety of drug taking
10 interesting things about alcohol and other drugs that you might have misse...Andrew Brown
Including... commissioners plans to reduce spending on services, injecting drug users and HIV, smoking prevalence, proportion of new Europol cases relating to drugs, time people spend on OST, regional variation on emergency hospital admissions for alcohol related liver disease, prisoners use of substances and their relationship to the crimes committed, numbers accessing domestic violence refuges, single homeless people's use of drugs and alcohol
Interesting things about Alcohol and Other Drugs that you might have missed -...Andrew Brown
Drug-related deaths in England and Wales rose 20% between 2012 and 2013, with over half caused by opiates and 30% mentioning alcohol use. Drug deaths account for 1 in 7 deaths among people in their 20s and 30s. Local authorities in England spent over £400 million on substance misuse programs in 2013-14, with 57% directed to adult drug treatment and 20% to services for at-risk youth. Random drug testing found that 8% of UK prisoners tested positive for drugs in 2013-14, with some prisons reporting over 20% of inmates testing positive.
Presentation given relating to the HSCIC report 'Focus on the health and care of young people June 2015' by Kate Croft, HSCIC Head of Statistical Response Unit. This took place at the Health+Care event at London's ExCel, on Thursday 25 June 2015.
12 things we learnt about drug and alcohol treatment in Wales in 2014-15Andrew Brown
The document summarizes key statistics from the Welsh National Database for Substance Misuse about drug and alcohol treatment in Wales in 2014-2015. Some of the main findings include: referrals were highest among those aged 25-34 for both males and females; the most common sources of referrals were GPs, self-referrals, and criminal justice; cannabis and alcohol were the most common problematic substances; the number of people in treatment increased slightly from 2013-2014; and the most common treatment types delivered were psychosocial interventions, brief interventions, and harm reduction.
Interesting things about alcohol and other drugs - July 2016Andrew Brown
The document contains information from various sources about drugs, alcohol, and related harms. It includes statistics on deaths in custody, drug and alcohol prices in different regions, alcohol sales data showing cheap prices, drug use in prisons has increased significantly with almost daily use, childhood abuse is linked to various mental health and substance use issues later in life, injecting equipment provision outlets in Scotland have seen a large rise in attendances, approximately one in six people with drug dependence receive treatment globally, alcohol-related deaths are much higher in males than females and increase with age.
Smoking, drinking and drug use by young people in England [2017 update]Mentor
The document summarizes trends in smoking, drinking, and drug use among young people in England. It finds that rates of alcohol and tobacco consumption are declining, while rates of e-cigarette use are rising. Drug use peaks at age 15, with cannabis being the most commonly used illicit drug. New psychoactive substances were popular before being banned, but rates of use for these and other illicit drugs are generally low. The document advocates for comprehensive education programs in schools to build resilience, promote accurate social norms, and teach life skills to reduce substance use among youth.
- Smoking rates among 15-year-olds in Richmond are the highest in England, so services must target this age group. Pregnant women smoking rates increased last year, so services need to help more quit.
- The document analyzes how stop smoking services in Richmond can better support groups most affected by smoking, such as youth, pregnant women, and men.
- Due to declining performance of stop smoking services in Richmond, the equality impact assessment is being done to ensure the services support all groups equitably.
More young people in Canada are visiting EDs because of drinking alcoholΔρ. Γιώργος K. Κασάπης
More people are visiting emergency departments after drinking alcohol, a new study finds. Researchers looked at more than 765,000 ED visits in Ontario, Canada’s largest province, and found a 175% increase in such visits between 2003 and 2016 among 25- to 29-year-olds. That spiked to a 240% increase in alcohol-related ED visits for young women, who were also more likely than men to be under Canada’s legal drinking age of 19. For both young men and women, visiting the ED for alcohol-related problems also led to more hospital admissions than other types of ED visits. Other countries, including the U.S., have experienced similar increases in alcohol-related visits to the ED, the authors behind the new study write, urging more research into the reasons behind the growing trend.
10 interesting things about alcohol and other drugs that you may have missed ...Andrew Brown
Including a call for the NHS and social services to address stigma issues, some of the key statistics from the Chief Medical Officer for England's report, European data on drugs and people who go to prison, drink driving offences in Great Britain, a comparison between drink driving and drug driving in those who use substances, football and alcohol offences, Lithuania as a source of methamphetamine in the UK, and the recovery rate of those using IAPT services who are diagnosed with alcohol problems.
December 14 - 10 (more) interesting things about alcohol and other drugs you ...Andrew Brown
Including data on drug deaths as a proportion of all deaths of adults 15 - 43, the use of naloxone by ambulance crews in the East Midlands, dependencies of people in police cells, seizures of drugs and mobile phones in HMP Durham, victims of criminal exploitation, number of people using residential rehab, cultivation or illegal drugs in Scotland, number of possession and possession with intent to supply offences recorded in Scotland, global narcotic seizures by the Royal Navy, and % changes to the ABV of alcohol between 2011 and 2013
Drivers of drug and alcohol policy in the UKAndrew Brown
This document discusses several issues related to drug and alcohol policy in the UK, including:
1) Trends showing increasing rates of illicit drug use and drug-related deaths, particularly among females.
2) Concerns around new psychoactive substances, the dark net, and organized crime influencing drug supply and misuse.
3) Debates around integrating drug and alcohol treatment services, balancing medication-based treatment with other approaches, and supporting recovery.
4) Calls for potential reforms to drug and alcohol laws and regulation in light of international experiences.
The Young Addictions project in Oxfordshire aims to address alcohol and drug addiction among youth through assessment, treatment, rehabilitation, counseling, and family support services. It was set up by volunteers to provide confidential help to young people struggling with addiction and help their families. The project has benefited the community by providing a way for people to seek advice, and has helped individuals gain confidence and employment through recovering from addiction.
Drugs and Prison - Statistics from the last yearAndrew Brown
The Ministry of Justice have recently reported that more drugs are being found in prisons in England. These slides are a compilation of the data that we've seen on drugs and prison over the last year.
Interesting things about alcohol and other drugs - Feb 2016Andrew Brown
The document provides statistics and information about alcohol and drug use and related harms in the UK:
- The number of individuals disqualified from driving due to drink or drug driving offenses has increased each year from 2011 to 2015.
- Prisoners are much more likely than the general population to have experienced adverse childhood experiences like abuse, violence at home, and time in care, and to have issues like unemployment, homelessness, and mental health problems.
- Alcohol-related deaths have been decreasing in the UK overall since the early 2000s, though rates are still higher in northern regions of England and Scotland compared to southern regions.
I've been back over the data relating to alcohol in my 'interesting things' series of slide sets and picked out the most interesting ones for this year's Alcohol Awareness Week
6 things for the Education Select Committee to think aboutAndrew Brown
The Education Select Committee of the UK House of Commons are undertaking an inquiry into the mental health and wellbeing of children in the looked after system. Here are 6 things they should know...
Hepatocarcinoma today between guidelines and medical therapy. The role of sur...Gian Luca Grazi
Today more than ever, hepatocellular carcinoma therapy is experiencing profound and substantial changes.
The association atezolizumab (ATEZO) plus bevacizumab (BEVA) has demonstrated its effectiveness in the post-operative treatment of patients, improving the results that can be achieved with liver resections. This after the failure of the use of sorafenib in the already historic STORM study.
On the other hand, the prognostic classification of BCLC is now widely questioned. It is now well recognized that the indications for surgery for patients with hepatocellular carcinoma are certainly narrow in BCLC and no longer reflect what is common everyday clinical practice.
Today, the concept of multiparametric therapeutic hierarchy, which makes the management of patients with hepatocellular carcinoma much more flexible and allows the best therapy for the individual patient to be identified based on their clinical characteristics, is gaining more and more importance.
The presentation traces these profound changes that are taking place in recent years and offers a modern vision of the management of patients with hepatocellular carcinoma.
Descoperă Bucuria Vieții Sănătoase cu Jurnalul Fericirii Life Care - Iulie 2024!
Gata să te bucuri de o vară vibrantă și plină de energie? Life Care îți vine în ajutor cu Jurnalul Fericirii din Iulie 2024, un ghid complet pentru o viață armonioasă și echilibrată.
Pe parcursul a cateva de pagini pline de informații utile și inspirație, vei descoperi:
Sfaturi practice pentru o alimentație sănătoasă:
Rețete delicioase și ușor de preparat: Bucură-te de preparate gustoase și nutritive, perfecte pentru zilele călduroase de vară.
Recomandări pentru o alimentație echilibrată: Asigură-ți aportul necesar de nutrienți esențiali pentru un organism sănătos și plin de vitalitate.
Sfaturi pentru alegeri alimentare inteligente: Învață cum să faci cumpărături sănătoase și să eviți tentațiile nesănătoase.
Trucuri pentru un stil de viață activ:
Rutine de exerciții fizice adaptate nevoilor tale: Găsește antrenamente potrivite pentru a te menține în formă și energic pe tot parcursul verii.
Idei de activități în aer liber: Descoperă modalități distractive de a te bucura de vremea frumoasă și de a petrece timp de calitate cu cei dragi.
Sfaturi pentru un somn odihnitor: Asigură-ți un somn profund și reparator pentru a te trezi revigorat și pregătit pentru o nouă zi.
Sfaturi pentru o stare de bine mentală:
Tehnici de relaxare și gestionare a stresului: Învață cum să te relaxezi și să faci față provocărilor zilnice cu mai multă ușurință.
Sfaturi pentru cultivarea optimismului și a gândirii pozitive: Descoperă cum să abordezi viața cu o perspectivă optimistă și să atragi mai multă bucurie în ea.
Recomandări pentru a te conecta cu natura: Bucură-te de beneficiile naturii asupra stării tale mentale și emoționale.
Bonus:
Oferte exclusive la produsele Life Care: Beneficiază de reduceri și promoții speciale la o gamă largă de produse pentru o viață sănătoasă.
Concursuri și premii: Participă la concursuri distractive și câștigă premii valoroase.
Jurnalul Fericirii Life Care - Iulie 2024 este mai mult decât o simplă revistă. Este un ghid complet și personalizat pentru a te ajuta să obții o viață mai sănătoasă, mai fericită și mai plină de satisfacții.
Nu rata această șansă de a te bucura de vară la maximum! Descoperă Jurnalul Fericirii Life Care - Iulie 2024 astăzi!
Comandă-ți exemplarul acum și fă un pas important către o viață mai bună!
#JurnalulFericirii #LifeCare #Iulie2024 #ViataSanatoasa #Bunastare #Fericire #Oferte #Concursuri #Premii
Ontotext’s Clinical Trials Eligibility Design Assistant helps with one of the most challenging tasks in study design: selecting the proper patient population.
Chair and Presenter, Stephen V. Liu, MD, Benjamin Levy, MD, Jessica J. Lin, MD, and Prof. Solange Peters, MD, PhD, discuss NSCLC in this CME/MOC/NCPD/AAPA/IPCE activity titled “Decoding Biomarker Testing and Targeted Therapy in NSCLC: The Complete Guide for 2024.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/4bBb8fi. CME/MOC/NCPD/AAPA/IPCE credit will be available until July 1, 2025.
High Profile"*Call "*Girls in Kolkata ))86-075-754-83(( "*Call "*Girls in Kol...Nisha Malik Chaudhary
High Profile "*Call "*Girls in Kolkata ))86-075-754-83(( "*Call "*Girls in Kolkata Available
Kolkata "Call "Girls 74046-34175 "Call "Girl Number in Kolkata | A nutshell review for Hot "Call "Girls in Kolkata . MY experience was superb with them this is the only recommended "Call "Girls service in Kolkata "Call "Girls and again then Russian. so overall my practice was magnificent. The price is also moderate per hour. The plus point is the "Girl comes instantly to your lo"Cation doesn't matter you are in Bur Kolkata or al Nahda or Kolkata or any area she comes undeviatingly to your hotel room. Definitely recommend the "Call "Girls agency. A nutshell review for Hot "Call "Girls in Kolkata . MY experience was superb with them this is the only recommended "Call "Girls service in Kolkata with verified "Call "Girls . I am using their services from past 6 months they never ever disappointed me in any way. Let's just say if i asked them to provide me russian "Call "Girls they fulfilled my request or even beautiful "Call "Girls or indian "Call "Girls in Kolkata . They have their owen drivers who brings the "Call "Girls in less time in any area of Kolkata like bur Kolkata marina or jumeirah or even in jebel ali as well. I'm writing here everything after experience their services in all conditions.
POTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptxsouravpaul769171
Theoretically, gene therapy is the permanent solution for genetic diseases. But it has several complexities. At its current stage, it is not accessible to most people due to its huge cost. A breakthrough may come anytime and a day may come when almost every disease will have a gene therapy Gene therapy have the potential to revolutionize the practice of medicine.
Pharmacotherapy of Asthma and Chronic Obstructive Pulmonary Disease (COPD)HRITHIK DEY
This PowerPoint presentation provides an in-depth overview of the pharmacotherapy approaches for managing asthma and Chronic Obstructive Pulmonary Disease (COPD). It covers the pathophysiology of these respiratory conditions, the various classes of medications used, their mechanisms of action, indications, side effects, and the latest treatment guidelines. Designed for students, healthcare professionals, and anyone interested in respiratory pharmacology, this presentation offers a comprehensive understanding of current therapeutic strategies and advancements in the field.
A comparative study on uroculturome antimicrobial susceptibility in apparentl...Bhoj Raj Singh
The uroculturome indicates the profile of culturable microbes inhabiting the urinary tract, and it is often required to do a urine culture to find an effective antimicrobial to treat UTIs. This study targeted to understand the profile of culturable pathogens in the urine of apparently healthy (128) and humans with clinical UTIs (161). In urine samples from UTI cases, microbial counts were 1.2×104 ± 6.02×103 colony-forming units (cfu)/ mL, while in urine samples from apparently healthy humans, the average count was 3.33± 1.34×103 cfu/ mL. In eight samples (six from UTI cases and two from apparently healthy people) of urine, Candida (C. albicans 3, C. catenulata 1, C. krusei 1, C. tropicalis 1, C. parapsiplosis 1, C. gulliermondii 1) and Rhizopus species (1) were detected. Candida krusei was detected only in a single urine sample from a healthy person and C. albicans was detected both in urine of healthy and clinical UTI cases. Fungal strains were always detected with one or more types of bacteria. Gram-positive bacteria were more commonly (OR, 1.98; CI99, 1.01-3.87) detected in urine samples of apparently healthy humans, and Gram -ve bacteria (OR, 2.74; CI99, 1.44-5.23) in urines of UTI cases. From urine samples of 161 UTI cases, a total of 90 different types of microbes were detected and, 73 samples had only a single type of bacteria. In contrast, 49, 29, 3, 4, 1, and 2 samples had 2, 3, 4, 5, 6 and 7 types of bacteria, respectively. The most common bacteria detected in urine of UTI cases was Escherichia coli detected in 52 samples, in 20 cases as the single type of bacteria, other 34 types of bacteria were detected in pure form in 53 cases. From 128 urine samples of apparently healthy people, 88 types of microbes were detected either singly or in association with others, from 64 urine samples only a single type of bacteria was detected while 34, 13, 3, 11, 2 and 1 samples yielded 2, 3, 4, 5, 6 and seven types of microbes, respectively. In the urine of apparently healthy humans too, E. coli was the most common bacteria, detected in pure culture from 10 samples followed by Staphylococcus haemolyticus (9), S. intermedius (5), and S. aureus (5), and similar types of bacteria also dominated in cases of mixed occurrence, E. coli was detected in 26, S. aureus in 22 and S. haemolyticus in 19 urine samples, respectively. Gram +ve bacteria isolated from urine samples' irrespective of health status were more often (p, <0.01) resistant than Gram -ve bacteria to ajowan oil, holy basil oil, cinnamaldehyde, and cinnamon oil, but more susceptible to sandalwood oil (p, <0.01). However, for antibiotics, Gram +ve were more often susceptible than Gram -ve bacteria to cephalosporins, doxycycline, and nitrofurantoin. The study concludes that to understand the role of good and bad bacteria in the urinary tract microbiome more targeted studies are needed to discern the isolates at the pathotype level.
EXPERIMENTAL STUDY DESIGN- RANDOMIZED CONTROLLED TRIALRishank Shahi
Randomized controlled clinical trial is a prospective experimental study.
It essentially involves comparing the outcomes in two groups of patients treated with a test treatment and a control treatment, both groups are followed over the same period of time. Prepare a plan of study or protocol
a. Define clear objectives
b. State the inclusion and exclusion criteria of case
c. Determine the sample size, place and period of study
d. Design of trial (single blind, double blind and triple blind method)
2. Define study population: Most often the patients are chosen from hospital or from the community. For example, for a study for comparison of home and sanatorium treatment, open cases of tuberculosis may be chosen.
3. Selection of participants by defined criteria as per plan:
Selection of participants should be done with precision and should be precisely stated in writing so that it can be replicated by others. For example, out of open cases of tuberculosis those who fulfill criteria for inclusion may be selected (age groups, severity of disease and treatment taken or not, etc.)
Randomization ensures that participants have an equal chance to be assigned to one of two or more groups:
One group gets the most widely accepted treatment (standard treatment/ gold standard)
The other gets the new treatment being tested, which researchers hope and have reason to believe will be better than the standard treatment
Subject variation: First, there may be bias on the part of the participants, who may subjectively feel better or report improvement if they knew they were receiving a new form of treatment.
Observer bias: The investigator measuring the outcome of a therapeutic trial may be influenced if he knows beforehand the particular procedure or therapy to which the patient has been subjected.
Evaluation bias: There may be bias in evaluation - that is, the investigator(Analyzer) may subconsciously give a favorable report of the outcome of the trial.
Co-intervention:
participants use other therapy or change behavior
Study staff, medical providers, family or friends treat participants differently.
Biased outcome ascertainment:
participants may report symptoms or outcomes differently or physicians
Investigators may elicit symptoms or outcomes differently
A technique used to prevent selection bias by concealing the allocation sequence from those assigning participants to intervention groups, until the moment of assignment.
Allocation concealment prevents researchers from influencing which participants are assigned to a given intervention group.
All clinical trials must be approved by Institutional Ethics Committee before initiation
It is mandatory to register clinical trials with Clinical Trials Registry of India
Informed consent from all study participants is mandatory.
A preclinical trial is a stage of research that begins before clinical trials, and during which important feasibility and drug safety data are collected.
Following points high.
EXPERIMENTAL STUDY DESIGN- RANDOMIZED CONTROLLED TRIAL
Most interesting of 2015
1. Some of the most interesting
things about alcohol and
other drugs in 2015
Andrew Brown
@andrewbrown365
2. Estimated rate of high risk drug users in Great Britain,
per 1,000 population aged 15 to 64
Nearly 1 in 100 people between
ages of 15 - 64 in Great Britain is
thought to be a high risk drug user
Definition of a high risk drug use:
“injecting drug use or long-
duration/regular use of opioids,
cocaine and/or amphetamines”
Source: http://www.nta.nhs.uk/uploads/uk-focal-point-report-2014.pdf
3. In 2013-14 there were
47,900
assessments for children in need
where alcohol or other drugs were a
factor at initial assessment.
In 2013-14
435
children ran away from foster care
because of substance misuse
Source: https://www.gov.uk/government/statistics/characteristics-
of-children-in-need-2013-to-2014
Source: https://www.gov.uk/government/statistics/fostering-in-
england-1-april-2013-to-31-march-2014
4. Substance use by prisoners and links to offending
The results demonstrate that drugs are
a problem among prisoners, regardless
of age, in contrast to general
population figures (although older
prisoners who had used drugs were
more likely to link their offending with
their drug use). They also show that
older adult prisoners were more likely
to have taken Class A drugs before
custody. This suggests that older adults
and young adult drug users may
require different types of intervention
focused on their particular patterns of
drug use.
Source: https://www.gov.uk/government/publications/needs-and-characteristics-of-young-adults-in-custody
5. Substance misuse and mental health in prison
Prisoners with drug and/or
alcohol problems tend to have
even higher levels of mental
health problems than the rest
of the prison population.
RAPt service users present
with an average of 3.4 mental
health problems.
Source: http://bit.ly/1ArNoan
6. Substance misuse issues for adults and children in
prison
Adult prisoners Children in the secure estate
Source: Service specification No. 29: public health services for
people in prison
Source: https://www.justiceinspectorates.gov.uk/hmiprisons/wp-
content/uploads/sites/4/2015/07/HMIP-AR_2014-
15_TSO_Final1.pdf
7. When do people with substance use problems turn up at
hospital in acute need?
“We found that access to, and the quality of,
services after 5pm was not good enough.
Commissioners and providers should make
sure that they have the most appropriate
services with the staff that have the right
skills working at the times when people with
mental health needs are more likely to access
them.”
CQC - “Right here, right now – help, care and
support during a mental health crisis”Source: http://www.cqc.org.uk/sites/default/files/20150611_righthere_mhcrisiscare_full_3b.pdf
8. Proportion of drug and alcohol clients in concurrent
contact with mental health services
Source: http://fingertips.phe.org.uk/profile-group/mental-health/profile/drugsandmentalhealth
9. “There is still a struggle with the dual
needs of people with alcohol and
mental health issues; this becomes
very frustrating as people seem to fall
into a gap between services. It seems
that services can only work with a
person either with mental health or
addiction - not with the whole
person.”
Are there appropriate care pathways for people with
both mental health and alcohol problems?
Source: The Recovery Partnership Review of Alcohol Treatment Services
10. Number of current drug injectors admitted to first drug
treatment, by country
“A total of 12,909 current
drug injectors were admitted
to first drug treatment in
2011, with the United
Kingdom (34.8 %)
accounting for the largest
proportion of reported
cases, followed by the Czech
Republic (16.6 %), Italy (13.7
%), Greece (6.6 %), Spain (5.7
%) and Germany (5.0 %).”
Source: http://www.emcdda.europa.eu/publications/technical-reports/trends-in-injecting-drug-use
11. Merseyside Annual Drug Intervention Programme report
2014/15
Just over half of all successful drug tests
carried out in Merseyside in 2014/15 were
positive (51.0%).
Of the 4,923 positive tests the highest
proportion was seen among those testing
positive for opiates (51.8%) often in
combination with cocaine (38.8%).
Source: Merseyside Annual DIP report 14/15
12. The number and proportion of stop and searches carried out
by police relating to suspicion of drug offences
While the number of stop and
searches carried out on suspicion of
drug offences have halved since
2010/11, the proportion that they
make of all stop and searches has
risen by 9% points over the same
period.
Source: Police powers and procedures England and Wales year ending 31 March 2015
13. Age of first use of people in drug treatment in the UK
Source: http://www.emcdda.europa.eu/data/stats2015#displayTable:TDI-0197
14. Levels of Blood Borne Viruses amongst people who
inject drugs in England, Wales and Northern Ireland
“The impact of public health
interventions which aim to prevent
HIV and hepatitis C infection through
injecting drug use, such as needle and
syringe programmes and opiate
substitution therapy, has been shown
to be dependent on their coverage. In
addition to these interventions,
increasing the treatment of hepatitis
C infection in PWID should also
reduce the transmission of hepatitis C
among PWID.”
Source: https://www.gov.uk/government/statistics/people-who-inject-drugs-hiv-and-viral-hepatitis-monitoring
15. Less than half of deaths (43%) in opioid users are from
overdoses
There were more than
five and a half times the
number of deaths
amongst opioid users
than would be expected
in the general
population between
2005 and 2009
Source: National record linkage study of mortality for a large cohort of opioid users ascertained by drug treatment or criminal justice sources in
England, 2005–2009, Pierce, Matthias et al., Drug & Alcohol Dependence , Volume 146 , 17 - 23
http://www.drugandalcoholdependence.com/article/S0376-8716(14)01844-4/pdf
16. Proportion of females who had been a victim of domestic
violence prior to drug related death in Scotland (2013)
13% of all those dying from drug related
deaths were reported to have been a
victim of domestic violence at some point
prior to death.
Over four-fifths (81%) were female.
45 in every 100 women who died had
experienced domestic violence at some
point; this compares to 3 in every 100 men.
Therefore women were 14x more likely to
have experienced domestic violence.
Source: http://www.isdscotland.org/Health-Topics/Drugs-and-Alcohol-Misuse/Publications/data-tables.asp?id=1386#1386
17. 1,382 children in Scotland lost a parent to a drug related
death between 2009 and 2013
Almost half of females (47%) and a third of males
(32%) who died a drug-related death in Scotland
in 2013 had children aged under 16.
Female parents (37%) were more likely to be
living with their children at the time of death
than male parents (12%).
Of those who lived with children at the time of
their death, one in three (34%) were known to
use drugs intravenously.
Source: http://www.isdscotland.org/Health-Topics/Drugs-and-Alcohol-
Misuse/Publications/
18. The known physical and mental health conditions of
those dying from drug related causes in Scotland
Physical health conditions experienced in the six months prior
to drug related deaths in Scotland
Mental health conditions experienced in the six months prior to
drug related deaths in Scotland
Source: http://www.isdscotland.org/Health-Topics/Drugs-and-Alcohol-Misuse/Publications/data-tables.asp?id=1386#1386
19. Regulations to allow wider access to naloxone in
England from 1 October 2015
These Regulations will allow drug services to obtain
stocks of Naloxone Hydrochloride and supply it to
anyone requiring access for use in an emergency
involving a heroin overdose. This will include drug
users, their family members and carers. It will also
include other people likely to come into contact with
drug users such as hostel managers.
The expected impact on the public sector, charities
or voluntary bodies will be an increase in the
availability of naloxone and a reduction in fatal
opioid overdoses. It is expected that the cost
associated with this wider availability, e.g. training
and storage, would be minimal.
“These Regulations amend the Human
Medicines Amendment Regulations 2012
(“the 2012 Regulations”). They do so in
order to allow drug treatment services
provided by or on behalf of NHS bodies and
local authorities (LAs) to supply Naloxone
Hydrochloride for administration in
emergencies involving a heroin overdose.”
Source: http://www.legislation.gov.uk/uksi/2015/1503/memorandum/contents
20. Take home naloxone
National take home naloxone
schemes should aim to issue 20
times as many kits as there are
opiate-related deaths per annum;
and at least nine times as many.
In 2014 there were 1,786 deaths
recorded in England and Wales where
an opiate was involved, including 952
which mentioned heroin or morphine.
Meaning there should be 35,720 (and
a minimum of 16,074) naloxone-kits
issued issued across England and
Wales.
Source: Sheila M. Bird , Mahesh K. B. Parmar , John Strang, Take-
home naloxone to prevent fatalities from opiate-overdose:
Protocol for Scotland’s public health policy evaluation, and a new
measure to assess impact, Drugs: Education, Prevention and Policy
Vol. 22, Iss. 1, 2015
Source: Deaths related to drug poisoning in England and Wales,
2014 registrations (ONS 2015)
21. Mean percentage purity of cocaine and heroin seized by
police in England and Wales, 2003 to 2013
Source: http://www.nta.nhs.uk/uploads/uk-focal-point-report-2014.pdf
22. Mental health patients who die by suicide with known
history of drug or alcohol misuse
Of those suicides in England where a patient had been in
touch with mental health services in the previous 12
months over half (54%) had a history of drug and/or
alcohol misuse. On average there were 671 deaths a
year in this group.
In Scotland 69% of mental health patient suicides, had a
known history of drug and/or alcohol misuse, an
average of 168 deaths per year.
In Wales an average of 41 deaths per year were to
patients, 57% of suicides in mental health patients.
Source:
http://www.bbmh.manchester.ac.uk/cmhs/research/centreforsuicidepre
vention/nci/
23. Injection of NPS in Wales
“Injection of cathinones, particularly
in the groin area has led to an increase
in physical impacts: granular/gritty
lumps under the skin, profound
bruising, abscesses, deep vein
thrombosis, long-term stays in
intensive care units of up to 3 months,
amputations, severe weight loss and
requirement for major reconstructive
surgery to femoral veins. Increased
injection rates were also noted, going
from approximately 3 up to 15–20
times per day.”
Source: http://www.emcdda.europa.eu/publications/rapid/2015/drug-related-infectious-
diseases-in-europe
24. What do people in receipt of opioid substitution therapy
think about services?
Source: How can opioidsubstitutiontherapy (and drug treatment and recovery systems) be optimisedto maximise recovery outcomes for service users?
25. Kilos of cocaine and heroin seizures in England and
Wales
Three quarters of
cocaine (65%) and heroin
(66%) seized in 2014/15
was in quantities under
1g.
3% of cocaine and 2% of
heroin seized weighed
more than 500g.
Source: Seizures of drugs in England and Wales, financial year ending 2015
26. Rates of Drugs-related Death Rates Soon After Hospital-
discharge for People in the Treatment System in
Scotland
For the cohort of over 98,000 drug
treatment clients in Scotland, there is a
high drugs-related death [DRD] risk in the
28 days after hospital-discharge. Length of
hospital-stay had no effect on DRD-rate,
discharge-diagnosis had an effect (as did
reported misuse of alcohol) but neither was
as discriminatory as the behavioral risk-
factor of having ever injected.
Source: White SR, Bird SM, Merrall ELC, Hutchinson SJ (2015) Drugs-RelatedDeath Soonafter Hospital-Dischargeamong Drug Treatment Clients in Scotland: Record Linkage,
Validation,and Investigationof Risk-Factors. PLoS ONE 10(11): e0141073.doi:10.1371/journal.pone.0141073
http://journals.plos.org/plosone/article?id=info:doi/10.1371/journal.pone.0141073
27. Short-term outcomes for opiate and crack users
accessing treatment in England (1 of 2)
“Significant, and substantive,
improvements in most behavioural
measures were recorded, and were
achieved within a relatively short period
of time following enrolment in treatment.
The study demonstrates that these
successful outcomes continued to be the
norm for the English opiate- and/or crack-
user treatment population, despite a
doubling in the number of drug users
treated, and changes in referral patterns
and drug use profiles.”Source: Short-term outcomes for opiate and crack users accessing treatment: the
effects of criminal justice referral and crack use.
28. Short-term outcomes for opiate and crack users
accessing treatment in England (2 of 2)
“The results observed here
demonstrate that, in the face of
marked changes in the English drug
treatment population, the positive
improvement in behavioural
outcomes observed in previous
studies has been sustained. Positive
changes were observed in the short
term but did not necessarily equate to
abstention from all drug taking and
offending behaviour.”
Source: Short-term outcomes for opiate and crack users accessing treatment: the
effects of criminal justice referral and crack use.
29. Reported purity of brown heroin in Europe in 2013
Source: http://www.emcdda.europa.eu/data/stats2015#displayTable:PPP-77-0
30. Substance misuse in older people
The proportion of high-risk older
people (over 60 years of age) with
substance misuse problems that
don’t receive the treatment that
they require.
Source: Substance misuse in older people: an information guide, Royal College of
Psychiatrists