Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Nucleic acids and their analogues for biomedical applications

F Wang, P Li, HC Chu, PK Lo - Biosensors, 2022 - mdpi.com
Nucleic acids are emerging as powerful and functional biomaterials due to their molecular
recognition ability, programmability, and ease of synthesis and chemical modification …

Biointerface engineering with nucleic acid materials for biosensing applications

S Shi, J Chen, X Wang, M Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Molecular recognition at the biointerface plays a critical role in sensing molecular
interactions (eg, DNA hybridization) and extracellular changes, which can directly affect the …

DNA nanotechnology-enabled interfacial engineering for biosensor development

D Ye, X Zuo, C Fan - Annual Review of Analytical Chemistry, 2018 - annualreviews.org
Biosensors represent biomimetic analytical tools for addressing increasing needs in medical
diagnosis, environmental monitoring, security, and biodefense. Nevertheless, widespread …

DNA-based scaffolds for sensing applications

S Ranallo, A Porchetta, F Ricci - Analytical chemistry, 2018 - ACS Publications
DNA nanotechnology employs synthetic nucleic acid strands to design and engineer
nanoscale structural and functional systems of increasing complexity that may find …

DNA nanotechnology-enabled biosensors

J Chao, D Zhu, Y Zhang, L Wang, C Fan - Biosensors and Bioelectronics, 2016 - Elsevier
Biosensors employ biological molecules to recognize the target and utilize output elements
which can translate the biorecognition event into electrical, optical or mass-sensitive signals …

Recent progresses in DNA nanostructure-based biosensors for detection of tumor markers

R Huang, N He, Z Li - Biosensors and Bioelectronics, 2018 - Elsevier
DNA has emerged as a promising biomaterial for assembling a variety of nanostructures
based on its programmable base pairing. It also has other remarkable properties including …

Nucleic acid–based nanodevices in biological imaging

K Chakraborty, AT Veetil, SR Jaffrey… - Annual Review of …, 2016 - annualreviews.org
The nanoscale engineering of nucleic acids has led to exciting molecular technologies for
high-end biological imaging. The predictable base pairing, high programmability, and …

Target-responsive structural switching for nucleic acid-based sensors

DI Li, S Song, C Fan - Accounts of Chemical Research, 2010 - ACS Publications
Interest in the development of sensitive, selective, rapid, and cost-effective biosensors for
biomedical analysis, environmental monitoring, and the detection of bioterrorism agents is …

DNA nanotechnology‐based biosensors and therapeutics

L Shen, P Wang, Y Ke - Advanced healthcare materials, 2021 - Wiley Online Library
Over the past few decades, DNA nanotechnology engenders a vast variety of programmable
nanostructures utilizing Watson–Crick base pairing. Due to their precise engineering …