Objectives: to determine the effect of drugs with anti-cholinergic properties on relevant
health outcomes. Design: electronic published and unpublished literature/trial registries …

Context The cognitive side effects of medications with anticholinergic activity have been
documented among older adults in a variety of clinical settings. However, there has been no …

The use of medication with anticholinergic properties is widespread among older subjects.
Many drugs of common use such as antispasmodics, bronchodilators, antiarrhythmics …

Objective Use of anticholinergic drugs in older people is associated with increased risk of
cognitive decline and of dementia and death. Method We identified drugs widely used in …

Background Drugs with anticholinergic effects are associated with adverse events such as
delirium and falls as well as cognitive decline and loss of independence. Objective The aim …

OBJECTIVES: To determine whether the use of medications with possible and definite
anticholinergic activity increases the risk of cognitive impairment and mortality in older …

Background: In 2008, the Anticholinergic Cognitive Burden (ACB) scale was generated
through a combination of laboratory data, literature review, and expert opinion. This scale …

Objectives To measure the association between the use of drugs with anticholinergic
properties and cognitive performance in an elderly population, the PAQUID cohort. Methods …

Aim The aim was to investigate associations between drugs with anticholinergic effects
(DACEs) and cognitive impairment, falls and all‐cause mortality in older adults. Methods A …

Background the long-term effect of the use of drugs with anticholinergic activity on cognitive
function remains unclear. Methods we conducted a systematic review and meta-analysis of …