The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …

Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …

Photoinduced atom transfer radical polymerization (photo-ATRP) has risen to the forefront of
modern polymer chemistry as a powerful tool giving access to well-defined materials with …

Photoinduced reversible-deactivation radical polymerization (photo-RDRP) techniques offer
exceptional control over polymerization, providing access to well-defined polymers and …

Delivery of nucleic acids with viral and synthetic vectors has pioneered genetic
nanomedicine. Four-component lipid nanoparticles (LNPs) consisting of ionizable lipids …

Constructing artificial dynamic architectures inside cells to rationally interfere with organelles
is emerging as an efficient strategy to regulate the behaviors and fate of cells, thus providing …

Hierarchical materials that exhibit order over multiple length scales are ubiquitous in nature.
Because hierarchy gives rise to unique properties and functions, many have sought …

Efficient viral or nonviral delivery of nucleic acids is the key step of genetic nanomedicine.
Both viral and synthetic vectors have been successfully employed for genetic delivery with …

Combining synthetic polymers with RNA paves the way for creating RNA-based materials
with non-canonical functions. We have developed an acylation reagent that allows for direct …

The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …