DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

DNA-framework-based multidimensional molecular classifiers for cancer diagnosis

F Yin, H Zhao, S Lu, J Shen, M Li, X Mao, F Li… - Nature …, 2023 - nature.com
A molecular classification of diseases that accurately reflects clinical behaviour lays the
foundation of precision medicine. The development of in silico classifiers coupled with …

Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

DNA hydrogel-based gene editing and drug delivery systems

F Mo, K Jiang, D Zhao, Y Wang, J Song… - Advanced Drug Delivery …, 2021 - Elsevier
Deoxyribonucleic acid (DNA) is a promising synthesizer for precisely constructing almost
arbitrary geometry in two and three dimensions. Among various DNA-based soft materials …

Nanozyme-involved biomimetic cascade catalysis for biomedical applications

X Cai, L Jiao, H Yan, Y Wu, W Gu, D Du, Y Lin, C Zhu - Materials Today, 2021 - Elsevier
Enzyme cascade reactions in biological systems can effectively improve the catalytic
performances owing to their high local concentration, efficient mass transfer and reduced …

Glucose oxidase-integrated metal–organic framework hybrids as biomimetic cascade nanozymes for ultrasensitive glucose biosensing

W Xu, L Jiao, H Yan, Y Wu, L Chen, W Gu… - … applied materials & …, 2019 - ACS Publications
Nanozyme/natural enzyme hybrid plays a vital role in biosensing, therapy, and catalysis
owing to the integrated advantages in the selectivity of natural enzymes and controllable …

Building machines with DNA molecules

H Ramezani, H Dietz - Nature Reviews Genetics, 2020 - nature.com
In nature, DNA molecules carry the hereditary information. But DNA has physical and
chemical properties that make it attractive for uses beyond heredity. In this Review, we …

The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation

LJ Sweetlove, AR Fernie - Nature communications, 2018 - nature.com
Transient physical association between enzymes appears to be a cardinal feature of
metabolic systems, yet the purpose of this metabolic organisation remains enigmatic. It is …