DNA origami
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
DNA origami: scaffolds for creating higher order structures
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …
Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …
dynamic properties and nanoscale control. These nanostructures enable complex …
DNA-framework-based multidimensional molecular classifiers for cancer diagnosis
A molecular classification of diseases that accurately reflects clinical behaviour lays the
foundation of precision medicine. The development of in silico classifiers coupled with …
foundation of precision medicine. The development of in silico classifiers coupled with …
Chemistries for DNA nanotechnology
M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …
DNA hydrogel-based gene editing and drug delivery systems
Deoxyribonucleic acid (DNA) is a promising synthesizer for precisely constructing almost
arbitrary geometry in two and three dimensions. Among various DNA-based soft materials …
arbitrary geometry in two and three dimensions. Among various DNA-based soft materials …
Nanozyme-involved biomimetic cascade catalysis for biomedical applications
Enzyme cascade reactions in biological systems can effectively improve the catalytic
performances owing to their high local concentration, efficient mass transfer and reduced …
performances owing to their high local concentration, efficient mass transfer and reduced …
Glucose oxidase-integrated metal–organic framework hybrids as biomimetic cascade nanozymes for ultrasensitive glucose biosensing
Nanozyme/natural enzyme hybrid plays a vital role in biosensing, therapy, and catalysis
owing to the integrated advantages in the selectivity of natural enzymes and controllable …
owing to the integrated advantages in the selectivity of natural enzymes and controllable …
Building machines with DNA molecules
H Ramezani, H Dietz - Nature Reviews Genetics, 2020 - nature.com
In nature, DNA molecules carry the hereditary information. But DNA has physical and
chemical properties that make it attractive for uses beyond heredity. In this Review, we …
chemical properties that make it attractive for uses beyond heredity. In this Review, we …
The role of dynamic enzyme assemblies and substrate channelling in metabolic regulation
LJ Sweetlove, AR Fernie - Nature communications, 2018 - nature.com
Transient physical association between enzymes appears to be a cardinal feature of
metabolic systems, yet the purpose of this metabolic organisation remains enigmatic. It is …
metabolic systems, yet the purpose of this metabolic organisation remains enigmatic. It is …