Sample results64 results in the last year.
Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures
with dynamic properties and nanoscale control. These nanostructures enable
complex biophysical studies and the fabrication of next-generation therapeutic …
with dynamic properties and nanoscale control. These nanostructures enable
complex biophysical studies and the fabrication of next-generation therapeutic …
Nucleic Acid‐based Enzyme Cascades—Current Trends and Future Perspectives
The natural micro‐and nanoscale organization of biomacromolecules is a
remarkable principle within living cells, allowing for the control of cellular functions by
compartmentalization, dimensional diffusion and substrate channeling. In order to …
remarkable principle within living cells, allowing for the control of cellular functions by
compartmentalization, dimensional diffusion and substrate channeling. In order to …
Overcoming biological barriers by virus-like drug particles for drug delivery
Virus-like particles (VLPs) have natural structural antigens similar to those found in
viruses, making them valuable in vaccine immunization. Furthermore, VLPs have
demonstrated significant potential in drug delivery, and emerged as promising …
viruses, making them valuable in vaccine immunization. Furthermore, VLPs have
demonstrated significant potential in drug delivery, and emerged as promising …
DNA-framework-based multidimensional molecular classifiers for cancer diagnosis
A molecular classification of diseases that accurately reflects clinical behaviour lays
the foundation of precision medicine. The development of in silico classifiers coupled
with molecular implementation based on DNA reactions marks a key advance in …
the foundation of precision medicine. The development of in silico classifiers coupled
with molecular implementation based on DNA reactions marks a key advance in …
Self‐assembly Induced Enhanced Electrochemiluminescence of Copper Nanoclusters Using DNA Nanoribbon Templates
Copper nanoclusters (CuNCs) are attractive electrochemiluminescence (ECL)
emitters as Cu is comparatively inexpensive, nontoxic, and highly abundant.
However, their ECL yield is relatively low. Herein, we report that orderly self …
emitters as Cu is comparatively inexpensive, nontoxic, and highly abundant.
However, their ECL yield is relatively low. Herein, we report that orderly self …
Liposomal Enzyme Nanoreactors Based on Nanoconfinement for Efficient Antitumor Therapy
Enzymatic reactions can consume endogenous nutrients of tumors and produce
cytotoxic species and are therefore promising tools for treating malignant tumors.
Inspired by nature where enzymes are compartmentalized in membranes to achieve …
cytotoxic species and are therefore promising tools for treating malignant tumors.
Inspired by nature where enzymes are compartmentalized in membranes to achieve …
Targeting and microenvironment-activated nanoreactor for diabetic chronic wound healing via multienzyme cascade reactions
The development of cell-like nanoreactors with the ability to initiate biocatalytic
cascades under special conditions holds tremendous potential for therapeutic
applications. Herein, conformationally gated nanoreactors that respond to the acidic …
cascades under special conditions holds tremendous potential for therapeutic
applications. Herein, conformationally gated nanoreactors that respond to the acidic …
A closed-loop catalytic nanoreactor system on a transistor
Precision chemistry demands miniaturized catalytic systems for sophisticated
reactions with well-defined pathways. An ideal solution is to construct a nanoreactor
system functioning as a chemistry laboratory to execute a full chemical process with …
reactions with well-defined pathways. An ideal solution is to construct a nanoreactor
system functioning as a chemistry laboratory to execute a full chemical process with …
Nanotechnology-enabled immunogenic cell death for improved cancer immunotherapy
Tumor immunotherapy has revolutionized the field of oncology treatments in recent
years. As one of the promising strategies of cancer immunotherapy, tumor
immunogenic cell death (ICD) has shown significant potential for tumor therapy …
years. As one of the promising strategies of cancer immunotherapy, tumor
immunogenic cell death (ICD) has shown significant potential for tumor therapy …
Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales
DNA origami technology enables the precise assembly of well-defined two-
dimensional and three-dimensional nanostructures with DNA, an inherently
biocompatible material. Given their modularity and addressability, DNA origami …
dimensional and three-dimensional nanostructures with DNA, an inherently
biocompatible material. Given their modularity and addressability, DNA origami …