Synapse-specific structural plasticity that protects and refines local circuits during LTP and LTD
KM Harris, M Kuwajima… - Philosophical …, 2024 - royalsocietypublishing.org
Synapses form trillions of connections in the brain. Long-term potentiation (LTP) and long-
term depression (LTD) are cellular mechanisms vital for learning that modify the strength …
term depression (LTD) are cellular mechanisms vital for learning that modify the strength …
Activity-dependent diffusion trapping of AMPA receptors as a key step for expression of early LTP
A Nowacka, AM Getz… - Philosophical …, 2024 - royalsocietypublishing.org
This review focuses on the activity-dependent diffusion trapping of α-amino-3-hydroxy-5-
methyl-4-isoxazolepropionic acid receptors (AMPARs) as a crucial mechanism for the …
methyl-4-isoxazolepropionic acid receptors (AMPARs) as a crucial mechanism for the …
A New Phase for WNK Kinase Signaling Complexes as Biomolecular Condensates
CR Boyd-Shiwarski, DJ Shiwarski… - Physiology, 2024 - journals.physiology.org
The purpose of this review is to highlight transformative advances that have been made in
the field of biomolecular condensates with special emphasis on condensate material …
the field of biomolecular condensates with special emphasis on condensate material …
SHP2 regulates GluA2 tyrosine phosphorylation required for AMPA receptor endocytosis and mGluR-LTD
S Lee, J Kim, HH Ryu, H Jang… - Proceedings of the …, 2024 - National Acad Sciences
Posttranslational modifications regulate the properties and abundance of synaptic α-amino-
3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors that mediate fast excitatory …
3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors that mediate fast excitatory …
Shifting rules in a brain disorder
D Choquet - Science, 2024 - science.org
The synaptic Ras/Rap guanosine triphosphatase (GTPase)–activating protein (SynGAP)
plays substantial, albeit still elusive, roles in synaptic function. SynGAP has attracted …
plays substantial, albeit still elusive, roles in synaptic function. SynGAP has attracted …
The role of liprin-α1 phosphorylation in its liquid-liquid phase separation: regulation by PPP2R5D/PP2A holoenzyme
A Mayer, R Derua, E Spahn, I Verbinnen, Y Zhang… - bioRxiv, 2024 - biorxiv.org
Liprin-alpha1 is a widely expressed scaffolding protein responsible for regulating cellular
processes such as focal adhesion, cell motility, and synaptic transmission. Liprin-alpha1 …
processes such as focal adhesion, cell motility, and synaptic transmission. Liprin-alpha1 …
CTNND2 regulation by the SRGAP2 protein family links human evolution to synaptic neoteny
N Assendorp, M Fossati, B Libé-Philippot… - bioRxiv, 2022 - biorxiv.org
Human-specific genes are potential drivers of brain evolution. Among them, SRGAP2C
contributes to distinct features by extending the period of synaptic maturation and increasing …
contributes to distinct features by extending the period of synaptic maturation and increasing …
A structural role for SynGAP
D Yates - Nature Reviews Neuroscience, 2024 - nature.com
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