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Yi Zhu
Yi Zhu
Assistant Professor, Mayo Clinic
Verified email at mayo.edu - Homepage
Title
Cited by
Year
Senolytics combat COVID-19 in aging
X Zhang, M Suda, Y Zhu
Nature aging 3 (7), 762-763, 2023
2023
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis
JN Farr, D Saul, ML Doolittle, J Kaur, JL Rowsey, SJ Vos, MN Froemming, ...
The Journal of clinical investigation 133 (8), 2023
262023
Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance
X Zhang, VM Pearsall, CM Carver, EJ Atkinson, BDS Clarkson, EM Grund, ...
Nature communications 13 (1), 5671, 2022
442022
Cellular senescence: a key therapeutic target in aging and diseases
L Zhang, LE Pitcher, MJ Yousefzadeh, LJ Niedernhofer, PD Robbins, ...
The Journal of Clinical Investigation 132 (15), 2022
1732022
Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition
M Rahman, I Olson, M Mansour, LP Carlstrom, R Sutiwisesak, R Saber, ...
Molecular Cancer Research 20 (6), 938-948, 2022
322022
Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans
Y Zhu, LGPL Prata, EOW Gerdes, JME Netto, T Pirtskhalava, N Giorgadze, ...
EBioMedicine, 103912, 2022
392022
Development of a novel senolytic by precise disruption of FOXO4-p53 complex
U Tripathi, S Chaib, EOW Gerdes, KA Hogan, Y Zhu
EBioMedicine 74, 2021
42021
Fisetin for COVID‐19 in skilled nursing facilities: Senolytic trials in the COVID era
BP Verdoorn, TK Evans, GJ Hanson, Y Zhu, LGP Langhi Prata, ...
Journal of the American Geriatrics Society 69 (11), 3023-3033, 2021
422021
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3
U Tripathi, R Nchioua, LGPL Prata, Y Zhu, EOW Gerdes, N Giorgadze, ...
Aging (Albany NY) 13 (18), 21838, 2021
652021
Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders
RM LABERGE, J Campisi, A DAVALOS, M DEMARIA, N David, ...
22021
Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies
S Suvakov, R Ghamrawi, H Cubro, H Tu, WM White, YSB Tobah, NM Milic, ...
EBioMedicine 70, 103536, 2021
272021
Treating liver disease by selectively eliminating senescent cells
RM Laberge, J Campisi, M Demaria, N David, JL Kirkland, T Tchkonia, ...
US Patent App. 17/114,379, 2021
2021
Senolytics reduce coronavirus-related mortality in old mice
CD Camell, MJ Yousefzadeh, Y Zhu, LGPL Prata, MA Huggins, M Pierson, ...
Science, 2021
2212021
An aged immune system drives senescence and ageing of solid organs
MJ Yousefzadeh, RR Flores, Y Zhu, ZC Schmiechen, RW Brooks, ...
Nature 594 (7861), 100-105, 2021
4892021
Mechanisms of vascular dysfunction in the interleukin-10–deficient murine model of preeclampsia indicate nitric oxide dysregulation
H Cubro, KA Nath, S Suvakov, O Garcia-Valencia, S Parashuram, ...
Kidney international 99 (3), 646-656, 2021
152021
Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice
M Ogrodnik, SA Evans, E Fielder, S Victorelli, P Kruger, H Salmonowicz, ...
Aging Cell 20 (2), e13296, 2021
2412021
Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue
BM Hall, AS Gleiberman, E Strom, PA Krasnov, D Frescas, S Vujcic, ...
Aging cell 19 (10), e13219, 2020
232020
Compositions for use in the treatment of senescence-assiocated disease and disorders
RM LABERGE, J Campisi, A DAVALOS, M DEMARIA, N David, ...
2020
The senescence-associated secretome as an indicator of age and medical risk
MJ Schafer, X Zhang, A Kumar, EJ Atkinson, Y Zhu, S Jachim, DL Mazula, ...
JCI insight 5 (12), 2020
2242020
Discovery, development, and future application of senolytics: theories and predictions
EO Wissler Gerdes, Y Zhu, T Tchkonia, JL Kirkland
The FEBS journal 287 (12), 2418-2427, 2020
1372020
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Articles 1–20