Walaa Aziz

Objective To estimate the incidence of myocardial infarction with nonobstructive coronary arteries (MINOCA) among Egyptian cases with acute myocardial infarction (AMI) and to evaluate the role of neutrophilic elastase in AMI cases. Background Previous research studies have declared that MINOCA is a syndrome with angiographic normal or near-normal coronary arteries but had evidence of MI clinically, which has many causes. Patients and methods To reach the goal of this research, a group study was designed. A total of 627 cases admitted at Cardiology Department of Faculty of Medicine Menoufia University and National Heart Institute in the period from February 2019 to July 2019 were included. Cases were divided into two groups: group 1 included AMI cases with obstructive coronary artery disease group, and group 2 included AMI cases with nonobstructive coronary artery disease (MINOCA group). All cases were subjected to (a) full history taking; (b) clinical examination; (c) laboratory inv...

Cardiac iron toxicity is the leading cause of death among β-halassaemia major (TM) patients. Once heart failure becomes overt, it is difficult to reverse. To investigate non-overt cardiac dysfunctions in TM patients using pulsed wave Tissue Doppler Imaging (TD I) and its relation to iron overload and brain natriuretic peptide (BNP). Thorough clinical, conventional echo and pulsed wave TDI parameters were compared between asymptomatic 25 β-TM patients and 20 age and gender matched individuals. Serum ferritin and plasma BNP levels were assayed by ELISA. TM patients had significant higher mitral inflow early diastolic (E) wave and non significant other conventional echo parameters. In the patient group, pulsed wave TDI revealed systolic dysfunctions, in the form of significant higher isovolumetric contraction time (ICT), and lower ejection time (E T), with diastolic dysfunction in the form of higher isovolumetric relaxation time (IRT), and lower mitral annulus early diastolic velocity ...