Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells (Q33831940)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15931392%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells (English)

1 reference

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12 January 2020

author

Christopher A. Klebanoff

2

1 reference

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12 January 2020

Douglas Palmer

3

1 reference

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12 January 2020

Nicholas P. Restifo

10

1 reference

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12 January 2020

9

Steven A Rosenberg

1 reference

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12 January 2020

4

Claudia Wrzesinski

1 reference

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12 January 2020

1

Luca Gattinoni

1 reference

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12 January 2020

5

Keith Kerstann

1 reference

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12 January 2020

8

Marc R Theoret

1 reference

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12 January 2020

author name string

Zhiya Yu

6

1 reference

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12 January 2020

Steven E Finkelstein

7

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12 January 2020

language of work or name

English

0 references

publication date

1 June 2005

1 reference

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Journal of Clinical Investigation

12 January 2020

published in

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12 January 2020

volume

115

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12 January 2020

issue

6

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12 January 2020

page(s)

1616-1626

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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

12 January 2020

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Vaccine-stimulated, adoptively transferred CD8+ T cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction.

4 July 2018

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4 July 2018

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4 July 2018

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Transition of late-stage effector T cells to CD27+ CD28+ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy

4 July 2018

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4 July 2018

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Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo.

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

4 July 2018

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4 July 2018

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Cell death: critical control points

4 July 2018

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Homing and cellular traffic in lymph nodes

4 July 2018

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Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

4 July 2018

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CD27 Promotes Survival of Activated T Cells and Complements CD28 in Generation and Establishment of the Effector T Cell Pool

4 July 2018

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Transregulation of memory CD8 T-cell proliferation by IL-15Rα+ bone marrow–derived cells

4 July 2018

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4 July 2018

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Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

4 July 2018

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4 July 2018

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Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3.

4 July 2018

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Lineage relationship and protective immunity of memory CD8 T cell subsets

4 July 2018

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4 July 2018

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

4 July 2018

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Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells

4 July 2018

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Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1)

4 July 2018

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Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells

4 July 2018

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4 July 2018

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Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

4 July 2018

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Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells

4 July 2018

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A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma

4 July 2018

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Homeostasis of naïve, effector and memory CD8 T cells

4 July 2018

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Transduction of an IL-2 gene into human melanoma-reactive lymphocytes results in their continued growth in the absence of exogenous IL-2 and maintenance of specific antitumor activity

4 July 2018

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Migratory properties of naive, effector, and memory CD8(+) T cells

4 July 2018

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Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes

4 July 2018

1 reference

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CD27 is required for generation and long-term maintenance of T cell immunity

4 July 2018

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Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

4 July 2018

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Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes

4 July 2018

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4 July 2018

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Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy

4 July 2018

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Extensive replicative capacity of human central memory T cells

4 July 2018

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Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

29 October 2018

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A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen

29 October 2018

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The fraction of perforin-expressing HIV-specific CD8 T cells is a marker for disease progression in HIV infection

29 October 2018

1 reference

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Viral infections induce abundant numbers of senescent CD8 T cells.

29 October 2018

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Isolation based on L-selectin expression of immune effector T cells derived from tumor-draining lymph nodes.

29 October 2018

1 reference

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Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15931392

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15931392

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15931392

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI24480

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15931392%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15931392%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PubMed publication ID

15931392

1 reference