1) The mechanism of action of Body Waves involves biological systems resonating with bio-physical information and regulating processes through reciprocal interaction.
2) Analogous to Weismann's Barrier Theory in agriculture, it is proposed that cell receptors can help transmit this information by getting into resonance with electron transport systems in the cell.
3) Regulation diseases as described by Jurgen Schole involve classifying diseases based on their etiology and pathogenesis into homologous, heterologous, or cascading patterns to better understand imbalances at different levels (psyche, metabolism, matter) that manifest as disease.
Aging of the somatosensory system. a translational perspectiveFUAD HAZIME
This document discusses aging-related changes to the somatosensory system and their relationship to balance impairments in older adults. It examines age-related declines in muscle spindles, golgi tendon organs, articular and cutaneous receptors, and the corresponding sensory neurons and fibers. These changes are linked to declines in proprioception, vibration and touch sensation in the lower extremities. The article relates these basic science findings to clinical evidence of impaired balance in older adults and calls for further research clarifying the relationship between sensory impairment and balance issues.
Pathophysiologic and psychodynamics of disease causationNamita Batra
This document discusses key concepts related to disease, including common causes, pathophysiology, and psychodynamics. It also covers the body's attempts to maintain homeostasis and adapt to stressors through four main concepts: constancy, homeostasis, stress, and adaptation. Homeostasis refers to maintaining stability through feedback systems, while stress disrupts this balance. The body responds to stress physiologically through the sympathetic nervous system and hormonally through the hypothalamic-pituitary axis. Psychological responses to stress include anxiety, fear, anger, and depression. Adaptation occurs when coping mechanisms help re-establish equilibrium.
The document discusses principles of self-healing technology based on physical and thermodynamic theories. It proposes that health and disease are functions of positive and negative information respectively, received through nutrition, climate, social interactions and other means. Negative information can alter cell programming and characteristics, potentially causing illness, while positive information facilitates self-regulation and healing through neutralizing negative energy and restoring healthy cell functions and properties. The document outlines several proposed self-healing techniques utilizing the body's natural energy and information processes.
Biophysics is essential to progress in biology as it discovers how atoms are arranged in proteins and DNA to carry out biological functions. Biophysicists are determining the structures of proteins through experiments to understand how they perform various roles in the body like movement, senses, energy production, immunity and more. Understanding variations in proteins also helps with drug design and precision medicine. Biophysics has also revealed structures like DNA and how it serves as the genetic blueprint of life.
Psychoneuroimmunology is the study of the interaction between psychological processes, the nervous system, and the immune system. A study led by Professor Shamgar Ben-Eliyahu found that psychological and physiological stress throughout surgery impairs immune system functioning, which can promote cancer recurrence. Blocking stress hormones before and after surgery through drugs was shown in animal models to reduce cancer metastases and potentially increase long-term survival rates in cancer patients by up to 300% by boosting the immune system.
Recent advances in Kriya Sharir (Ayurveda Physiology)Kishor Patwardhan
Recent advances in systems biology, neuroendocrinology, immunology, tissue engineering, chronobiology, gut microbiota, pharmacogenomics, and the study of extra-gustatory taste receptors provide opportunities to better understand Ayurveda using a systems approach. A systems approach views the human body as a complex system of interconnected parts and aims to understand how biological processes function as a whole, rather than focusing only on reductionist studies of individual molecules.
(1) The document discusses integrating different perspectives in medicine, including systems biology, traditional Chinese medicine, and personalized preventative approaches.
(2) It emphasizes moving from treating diseases to promoting health, from general treatments to personalized care tailored to individual biomarkers and phenotypes.
(3) The future of medicine is seen as incorporating multiple dimensions like lifestyle, nutrition, alternative therapies alongside molecular diagnostics and targeted drugs into a comprehensive personalized health ecosystem.
pathophysiology and psychodynamics of disease causationPreet Kaur
Pathophysiology is the study of abnormal physiological processes in the body that cause or are caused by disease or injury. It involves understanding how and why normal anatomy and physiology is altered by the disease process. Any disruption to homeostasis, whether from internal or external factors, can potentially lead to physiological changes at the cellular level that may result in disease. Common disease processes studied in pathophysiology include genetic disorders, infections, inflammation, immune responses, cell injury and healing processes.
The document summarizes theories on the genetics of personality. It discusses Eysenck's three-factor model of personality and Gray's reinforcement sensitivity theory. Eysenck's model proposes three factors - extraversion, neuroticism, and psychoticism - which are associated with different brain systems. Gray's theory suggests three brain systems - fight-flight-freeze, behavioral inhibition, and behavioral approach - that underlie sensitivity to rewards and punishments and relate to traits like anxiety and impulsivity. Both theories view personality as influenced by biological factors and have informed research on linking traits to brain mechanisms.
Dissorders of regulation towards a systemic based treatment of alzheimers dis...Michael Changaris
This document outlines a theoretical model for understanding certain diseases as "disorders of regulation" caused by disruptions in the balanced functioning of biological systems. It focuses on telomerase, an enzyme that regulates cellular lifespan, as an example. Perturbations like stress, lifestyle factors, or toxins can dysregulate telomerase and disrupt the balance between systems. This increased vulnerability can lead to diseases like cancer, neurodegeneration, and autoimmunity when other triggers occur. Maintaining regulatory balance between biological systems may be key to preventing and treating such disorders.
Homeostatic mechanisms work to maintain steady internal conditions in the body. Negative feedback systems counteract changes, while positive feedback can amplify them. Homeostasis relies on receptors, chemical messengers, and signal transduction pathways between cells. Receptors detect messengers and trigger cellular responses through various regulatory mechanisms. Together these components allow the body to dynamically adapt to internal and external changes.
1. The document discusses risk factors, etiology, and the physiological response to stress in relation to disease causation and psychodynamics.
2. Key risk factors include genetic, age-related, environmental, and lifestyle factors that can increase one's vulnerability to illness. Etiology refers to the specific causes of a disease, which can include hereditary, congenital, inflammatory, infectious, metabolic, and traumatic factors.
3. When exposed to stress, the body has physiological, neurological, and hormonal responses like increased sympathetic nervous system activation, hypothalamic-pituitary-adrenal axis stimulation, and immune system changes to help maintain homeostasis. Prolonged stress can lead to exhaustion
The document discusses developing a functional model for restoring biological competency and systemic organic function. It proposes a metabolic optimization approach that views disease as altered metabolic processes affected by various physical, emotional, mental and spiritual factors. The goal is to make metabolisms as efficient as possible to achieve high levels of balance and organization for optimal health. A personalized program involves gathering information on an individual's current state and implementing therapies in a phased, hierarchical manner, starting with organ detoxification, then regeneration, and finally energetic balancing to restore electromagnetic flow.
This document discusses the ethical implications that arise from recent developments in molecular medicine, specifically genome sequencing and induced pluripotent stem cells. It outlines two competing paradigms of genetics - genetic determinism vs seeing phenotypes as resulting from genetic and epigenetic networks. The document argues that understanding human development as a complex, dynamic process rather than a genetic program has divergent ethical implications. It claims bioethics must engage in dialogue with science and critically analyze how new understandings of genetics shape perceptions of human life, health, disease, and the goals of medicine.
Cell sensitivity, non-linearity and inverse effectshome
This document reviews cellular mechanisms that could explain the effects of homeopathic remedies, even at very high dilutions. It discusses how cells are highly sensitive to ultra-low doses of stimuli and can respond in non-linear ways. Several studies show that homeopathic dilutions can modulate gene expression in cells. The document proposes that homeopathic remedies may act through allosteric regulation of proteins rather than direct chemical binding, eliciting dynamic conformational changes that enhance or inhibit cellular functions. Overall, the principles of homeopathy, such as the use of highly diluted substances, may be consistent with modern knowledge of biological sensitivity and complexity at the molecular, cellular, and systemic levels.
The document discusses principles of self-healing technology based on physical and thermodynamic theories. It proposes that health and disease are functions of positive and negative information respectively, received through nutrition, climate, social interactions and other means. Negative information can alter cell programming and characteristics, potentially causing illness, while positive information facilitates self-regulation and healing through natural processes in the body. The document outlines several proposed methods for harnessing bodily energy and improving efficiency to support self-healing, such as increasing core temperature and reducing entropy.
Jan van der Greef argues that current healthcare is limited by its focus on reductionism and "one-size-fits-all" treatments. A systems view is needed that considers the dynamic relationships and organization within complex biological systems. This will enable personalized health strategies based on biomarkers and molecular fingerprints, moving beyond single drug treatments. Measuring coherence and interactions across biological, environmental and social systems can provide insights into health and disease. Diagnosis is key to stratifying patients and moving towards a new model of healthcare focused on resilience, wellness promotion and human-centered, participatory care within a systems framework.
1) Disease is necessary for organic progress and evolution according to the author. Complex genetic and structural changes that occur during development reflect the pathogenic processes that ancestral embryos were exposed to during phylogeny.
2) Pathogenic factors can damage cells and disrupt homeostasis, leading to "erroneous" or "alternative" expression of genetic information that provides evolutionary material. Micro-changes in damaged cells' genetic activity that are adaptive can be selected for.
3) Typical pathogenic processes were tools for creating new forms during organic development and progress, according to the author. Diseaseful organisms were the "hopeful patients" that drove progressive evolution.
1) Disease is necessary for organic progress and evolution according to the author. Stable disturbances of homeostasis, called disease, allow for reorganization of internal structures and complexity.
2) Pathogenic factors can damage cells and disrupt genetic processes, leading to "erroneous" or alternative expression of genetic information that provides material for evolution. Micro-changes from damaged cells are selected by natural selection.
3) Ontogeny involves many pathological processes that resemble those that ancestral embryos experienced, reflecting the role of disease in phylogenetic development. Complex changes in development are a result of past pathological exposures.
In September 1944, the Netherlands was still under Nazi control near the end of World War II. The Allied Forces attempted to liberate the country with a railway strike, but this failed. In response, the German government imposed a food embargo on the Netherlands, coinciding with a harsh winter that led to poor crops. This caused a famine, with daily calorie intake dropping drastically from over 2,300 to just 1,000 initially.
1. P4 medicine requires vast amounts of data because biology and disease are incredibly complex, arising from random and chaotic evolutionary processes that build upon existing structures in complex ways, like Rube Goldberg machines.
2. Viewing biology through an informational lens helps organize vast amounts of data by recognizing two types of biological information - genetic and environmental - that are integrated across molecular, cellular, tissue, and systemic levels in hierarchical networks and machines.
3. Studying the progression of prion disease in mice revealed over 7,000 differentially expressed genes across disease progression, which was reduced to around 300 genes most associated with neurodegeneration through various subtractions. These 300 genes mapped to four major biological networks involved in
Quantum medicine brings together insights from quantum physics and multidisciplinary research to show that the human body is regulated by the human energy system. It integrates various natural medicine approaches and modern technology to produce and measure energy variations to restore health. Key aspects of quantum medicine include homeopathy, holistic methods, electrodermal screening, body scanning, bio-resonance, informational medicine, and examining vibrational frequencies and biophysics at the quantum level. The goal is to reestablish coherent cellular communication and proper information flow through the body's energy channels.
Noise in multiple sclerosis: unwanted and necessaryMutiple Sclerosis
Isabella Bordi, Vito A G Ricigliano, Renato Umeton, Giovanni Ristori, Francesca Grassi, Andrea Crisanti, Alfonso Sutera, and Marco Salvetti
As our knowledge about the etiology of multiple sclerosis (MS) increases, deterministic paradigms appear insufficient to describe the pathogenesis of the disease, and the impression is that stochastic phenomena (i.e. random events not necessarily resulting in disease in all individuals) may contribute to the development of MS. However, sources and mechanisms of stochastic behavior have not been investigated and there is no proposed framework to incorporate nondeterministic processes into disease biology. In this report, we will first describe analogies between physics of nonlinear systems and cell biology, showing how small-scale random perturbations can impact on large-scale phenomena, including cell function. We will then review growing and solid evidence showing that stochastic gene expression (or gene expression "noise") can be a driver of phenotypic variation. Moreover, we will describe new methods that open unprecedented opportunities for the study of such phenomena in patients and the impact of this information on our understanding of MS course and therapy.
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA.docxsleeperharwell
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA M M E D . O R G ✦ VO L . 2 , N O. 6 ✦ N OV E M B E R / D E C E M B E R 2 0 0 4
576
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA M M E D . O R G ✦ VO L . 2 , N O. 6 ✦ N OV E M B E R / D E C E M B E R 2 0 0 4
576
The Biopsychosocial Model 25 Years Later:
Principles, Practice, and Scientifi c Inquiry
ABSTRACT
The biopsychosocial model is both a philosophy of clinical care and a practical
clinical guide. Philosophically, it is a way of understanding how suffering, disease,
and illness are affected by multiple levels of organization, from the societal to the
molecular. At the practical level, it is a way of understanding the patient’s subjec-
tive experience as an essential contributor to accurate diagnosis, health outcomes,
and humane care. In this article, we defend the biopsychosocial model as a nec-
essary contribution to the scientifi c clinical method, while suggesting 3 clarifi ca-
tions: (1) the relationship between mental and physical aspects of health is com-
plex—subjective experience depends on but is not reducible to laws of physiology;
(2) models of circular causality must be tempered by linear approximations when
considering treatment options; and (3) promoting a more participatory clinician-
patient relationship is in keeping with current Western cultural tendencies, but may
not be universally accepted. We propose a biopsychosocial-oriented clinical prac-
tice whose pillars include (1) self-awareness; (2) active cultivation of trust; (3) an
emotional style characterized by empathic curiosity; (4) self-calibration as a way to
reduce bias; (5) educating the emotions to assist with diagnosis and forming thera-
peutic relationships; (6) using informed intuition; and (7) communicating clinical
evidence to foster dialogue, not just the mechanical application of protocol. In con-
clusion, the value of the biopsychosocial model has not been in the discovery of
new scientifi c laws, as the term “new paradigm” would suggest, but rather in guid-
ing parsimonious application of medical knowledge to the needs of each patient.
Ann Fam Med 2004;2:576-582. DOI: 10.1370/afm.245.
GEORGE ENGEL’S LEGACY
T
he late George Engel believed that to understand and respond
adequately to patients’ suffering—and to give them a sense of being
understood—clinicians must attend simultaneously to the biologi-
cal, psychological, and social dimensions of illness. He offered a holistic
alternative to the prevailing biomedical model that had dominated indus-
trialized societies since the mid-20th century.1 His new model came to be
known as the biopsychosocial model. He formulated his model at a time
when science itself was evolving from an exclusively analytic, reductionis-
tic, and specialized endeavor to become more contextual and cross-disci-
plinary.2-4 Engel did not deny that the mainstream of biomedical research
had fostered important advances .
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA.docxblondellchancy
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA M M E D . O R G ✦ VO L . 2 , N O. 6 ✦ N OV E M B E R / D E C E M B E R 2 0 0 4
576
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA M M E D . O R G ✦ VO L . 2 , N O. 6 ✦ N OV E M B E R / D E C E M B E R 2 0 0 4
576
The Biopsychosocial Model 25 Years Later:
Principles, Practice, and Scientifi c Inquiry
ABSTRACT
The biopsychosocial model is both a philosophy of clinical care and a practical
clinical guide. Philosophically, it is a way of understanding how suffering, disease,
and illness are affected by multiple levels of organization, from the societal to the
molecular. At the practical level, it is a way of understanding the patient’s subjec-
tive experience as an essential contributor to accurate diagnosis, health outcomes,
and humane care. In this article, we defend the biopsychosocial model as a nec-
essary contribution to the scientifi c clinical method, while suggesting 3 clarifi ca-
tions: (1) the relationship between mental and physical aspects of health is com-
plex—subjective experience depends on but is not reducible to laws of physiology;
(2) models of circular causality must be tempered by linear approximations when
considering treatment options; and (3) promoting a more participatory clinician-
patient relationship is in keeping with current Western cultural tendencies, but may
not be universally accepted. We propose a biopsychosocial-oriented clinical prac-
tice whose pillars include (1) self-awareness; (2) active cultivation of trust; (3) an
emotional style characterized by empathic curiosity; (4) self-calibration as a way to
reduce bias; (5) educating the emotions to assist with diagnosis and forming thera-
peutic relationships; (6) using informed intuition; and (7) communicating clinical
evidence to foster dialogue, not just the mechanical application of protocol. In con-
clusion, the value of the biopsychosocial model has not been in the discovery of
new scientifi c laws, as the term “new paradigm” would suggest, but rather in guid-
ing parsimonious application of medical knowledge to the needs of each patient.
Ann Fam Med 2004;2:576-582. DOI: 10.1370/afm.245.
GEORGE ENGEL’S LEGACY
T
he late George Engel believed that to understand and respond
adequately to patients’ suffering—and to give them a sense of being
understood—clinicians must attend simultaneously to the biologi-
cal, psychological, and social dimensions of illness. He offered a holistic
alternative to the prevailing biomedical model that had dominated indus-
trialized societies since the mid-20th century.1 His new model came to be
known as the biopsychosocial model. He formulated his model at a time
when science itself was evolving from an exclusively analytic, reductionis-
tic, and specialized endeavor to become more contextual and cross-disci-
plinary.2-4 Engel did not deny that the mainstream of biomedical research
had fostered important advances ...
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA.docxronak56
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA M M E D . O R G ✦ VO L . 2 , N O. 6 ✦ N OV E M B E R / D E C E M B E R 2 0 0 4
576
A N NA L S O F FA M I LY M E D I C I N E ✦ W W W. A N N FA M M E D . O R G ✦ VO L . 2 , N O. 6 ✦ N OV E M B E R / D E C E M B E R 2 0 0 4
576
The Biopsychosocial Model 25 Years Later:
Principles, Practice, and Scientifi c Inquiry
ABSTRACT
The biopsychosocial model is both a philosophy of clinical care and a practical
clinical guide. Philosophically, it is a way of understanding how suffering, disease,
and illness are affected by multiple levels of organization, from the societal to the
molecular. At the practical level, it is a way of understanding the patient’s subjec-
tive experience as an essential contributor to accurate diagnosis, health outcomes,
and humane care. In this article, we defend the biopsychosocial model as a nec-
essary contribution to the scientifi c clinical method, while suggesting 3 clarifi ca-
tions: (1) the relationship between mental and physical aspects of health is com-
plex—subjective experience depends on but is not reducible to laws of physiology;
(2) models of circular causality must be tempered by linear approximations when
considering treatment options; and (3) promoting a more participatory clinician-
patient relationship is in keeping with current Western cultural tendencies, but may
not be universally accepted. We propose a biopsychosocial-oriented clinical prac-
tice whose pillars include (1) self-awareness; (2) active cultivation of trust; (3) an
emotional style characterized by empathic curiosity; (4) self-calibration as a way to
reduce bias; (5) educating the emotions to assist with diagnosis and forming thera-
peutic relationships; (6) using informed intuition; and (7) communicating clinical
evidence to foster dialogue, not just the mechanical application of protocol. In con-
clusion, the value of the biopsychosocial model has not been in the discovery of
new scientifi c laws, as the term “new paradigm” would suggest, but rather in guid-
ing parsimonious application of medical knowledge to the needs of each patient.
Ann Fam Med 2004;2:576-582. DOI: 10.1370/afm.245.
GEORGE ENGEL’S LEGACY
T
he late George Engel believed that to understand and respond
adequately to patients’ suffering—and to give them a sense of being
understood—clinicians must attend simultaneously to the biologi-
cal, psychological, and social dimensions of illness. He offered a holistic
alternative to the prevailing biomedical model that had dominated indus-
trialized societies since the mid-20th century.1 His new model came to be
known as the biopsychosocial model. He formulated his model at a time
when science itself was evolving from an exclusively analytic, reductionis-
tic, and specialized endeavor to become more contextual and cross-disci-
plinary.2-4 Engel did not deny that the mainstream of biomedical research
had fostered important advances .
Feiyuebio research direction includes metabolomics, signal transduction, neuroscience, and immunology. Metabolomics is the study of metabolites and their role in cellular processes like energy metabolism and biosynthesis. Signal transduction refers to the process of transmitting extracellular signals through intracellular biochemical cascades via receptors and signaling pathways. Neuroscience is the study of the nervous system, including the structure and function of the brain. Immunology charts the immune system's role in health and disease by studying the physiological and molecular characteristics of its components.
Quantum Medicine integrates various alternative medicine approaches with insights from quantum physics. It views the human body as controlled and regulated by the human energy system. Quantum Medicine uses modern technology to measure and produce quantum variations of energy to interact with and correct imbalances in the body's energetic flows, restoring health. It recognizes that cellular quantum coherence is essential for health and aims to reestablish cellular resonance when coherence is disturbed by disease. Information flow is also important, and Quantum Medicine seeks to reestablish the proper flow of information through the body's energy channels to promote health and self-healing.
The document discusses concepts from Buddhism related to taming the mind. It compares an uncontrolled, passionate mind to a rampaging wild elephant, noting how we are often ruled by desires, fears, and resentments in the same way. However, the Buddha taught that suffering arises from our untrained mental responses rather than external events. Through meditation and disciplining the mind, we can transform it from uncontrolled to stable and majestic, like a tamed elephant. With a trained mind, we can transform adversity into growth through "spiritual alchemy" rather than reacting with sullen forbearance.
A Mechanistic, Stochastic Model Helps Understand Multiple Sclerosis Course an...Mutiple Sclerosis
Isabella Bordi, Renato Umeton, Vito A. G. Ricigliano, Viviana Annibali, Rosella Mechelli, Giovanni Ristori, Francesca Grassi, Marco Salvetti, and Alfonso Sutera
Heritable and nonheritable factors play a role in multiple sclerosis, but their effect size appears too small, explaining relatively little about disease etiology. Assuming that the factors that trigger the onset of the disease are, to some extent, also those that generate its remissions and relapses, we attempted to model the erratic behaviour of the disease course as observed on a dataset containing the time series of relapses and remissions of 70 patients free of disease-modifying therapies. We show that relapses and remissions follow exponential decaying distributions, excluding periodic recurrences and confirming that relapses manifest randomly in time. It is found that a mechanistic model with a random forcing describes in a satisfactory manner the occurrence of relapses and remissions, and the differences in the length of time spent in each one of the two states. This model may describe how interactions between "soft" etiologic factors occasionally reach the disease threshold thanks to comparably small external random perturbations. The model offers a new context to rethink key problems such as "missing heritability" and "hidden environmental structure" in the etiology of complex traits.
This document introduces World of Anatomy and Physiology (WAP), which is a reference devoted to the study of human form and function. WAP contains over 650 entries covering topics from biographies of pioneers in anatomy and physiology to explanations of current developments in areas like embryology. The goal is to provide accessible explanations for a wide range of readers, from less experienced students to more advanced students and professionals. Anatomy studies body structures while physiology studies how the body's structures work and maintain life functions. Maintaining homeostasis, or internal equilibrium, is essential and involves complex interactions between organ systems and feedback mechanisms. The pace of scientific progress, like in areas of developmental and reproductive biology, presents challenges to keep references like WAP up
Magnesium may be an effective agent for treating hypoxic-ischemic brain injury. It can protect brain cells through multiple mechanisms: (1) it is an NMDA receptor blocker that reduces excitotoxicity, (2) it attenuates biochemical changes like ATP depletion and acidosis, and (3) it has anti-inflammatory and vasodilatory properties that can reduce edema. Magnesium's diverse physiological roles allow it to counteract the various pathways of injury better than other agents used singly. More research is still needed but magnesium shows promise as a "master drug" for brain resuscitation.
The Biology of the Many and the Health of the IndividualStephen Lewis
Although human biology studies humans scientifically, many human biologists work in healthcare. Human biology focuses on populations while healthcare helps individuals. With evolutionary medicine linking the two fields, human biology may need to understand individuals and disease at an individual level rather than just population levels. Reconstructing individuals as biological entities with interactions between various factors could help human biology understand health and disease in individuals.
Similar to Mechanism of action of the Body Wave (20)
The 10th DVFA Life Science Conference focused on digital transformation in healthcare. Topics included challenges and opportunities of digital transformation, connected diabetes management, increased data protection requirements, new business models in digital health, next generation sequencing, using smart data for better health outcomes, and a capital market perspective on digital health. There were presentations from industry experts and startup companies, as well as panel discussions on these topics.
The document summarizes a research project that aims to:
1. Test an HRV-based health monitoring system (IMI-HCS) under real-world conditions and integrate customer feedback from Europe.
2. Study the relationship between HRV parameters and nutritional state.
3. Describe benefits of the system for healthy and diseased clients and define group-specific details.
The document summarizes an upcoming conference on digital transformation in healthcare hosted by the Society of Investment Professionals in Germany. The 10th DVFA Life Science Conference will focus on challenges and opportunities around digital transformation in healthcare, with explosive growth in health data driving momentum in the digitalization of the healthcare sector. The conference will provide insights into topics like network medicine, electronic health records, medical apps/cloud computing, and EU data protection rules, with panels on new business models and capital market perspectives in digital health. It will feature industry experts as speakers and is aimed at professionals in life sciences, healthcare, and related fields.
Gerhard Lingg has extensive education and experience in alternative and integrative medicine. He received multiple doctorate degrees and has held professorships. His research focuses on areas like heart rate variability, herbal medicine, mobile health, and the effects of homeopathic remedies. He has published several books and papers, holds patents, and regularly presents at international conferences.
„Studieren, wie ich es will!“
JEDERZEIT - VON ÜBERALL - FLEXIBEL – UNGEBUNDEN
Mit unseren Angeboten bieten wir Studierenden über den ganzen Globus einen Zugang zu Bildung auf höchstem Niveau, interdisziplinärer Vernetzung und wissenschaftlichem Austausch.
Dual-degree Programme
This document provides information about blended and distance learning programs offered by Universidad Central de Nicaragua and Universidad Azteca. It describes a dual-degree Health Economics program that can be completed entirely online or through a blended model. The 3-year program awards an MSc and PhD in Health Sciences. It is designed for professionals in health-related fields and addresses challenges in health care.
This document provides information about blended and distance learning programs offered by Universidad Central de Nicaragua (UCN) and Universidad Azteca. It summarizes their dual-degree Health Economics program, which can be completed entirely online or through a blended model. The 2-year program awards an MSc from UCN and an MBA from Universidad Azteca, and covers topics like business administration, statistics, sociology, and health fields. It is conducted in English or German and costs 11,500-12,000 EUR in total tuition fees.
This research article summarizes a study that investigated the effects of homeopathically prepared thyroxin solutions on the metamorphosis of highland frogs from the two-legged stage. Researchers treated frogs with thyroxin that was diluted through steps of 1:50,000 to concentrations between 10-11 and 10-21 or with an analogously prepared water control. They found that frogs treated with the thyroxin solutions metamorphosed more slowly than the control frogs, taking 2-13.5% longer on average to reach the four-legged stage. This inverse effect compared to untreated thyroxin supported previous findings and the idea in homeopathy that highly diluted substances can produce effects opposite to the original substance.
This study examined the effects of craniosacral therapy (CST) on heart rate variability (HRV) in 31 patients with subjective discomforts. HRV was measured before and after a 30-minute control rest period and a 30-minute CST session on consecutive days using a mobile device. Standard deviation of heart rate intervals (SDNN) and total power (TP), indicators of autonomic nervous system activity, increased significantly after CST but not the control rest. Heart rate also decreased significantly after CST compared to rest. However, interactions between treatment and HRV changes were not fully statistically significant. The study provides preliminary evidence that CST may positively influence autonomic nervous system regulation.
This document outlines a Horizon 2020 proposal for a project called Nutriglob. The proposal was submitted by Prof. Dr. Wilhelm Mosgöller and Dr. Dr. Gerhard Lingg PhD for a PHC-26-2014 single-stage call under the topic area H2020-PHC-2014. The proposal number is SEP-210165258 and the project is proposed under the acronym Nutriglob.
Offene Kommunikation mit Todkranken und ihren Angehörigen – mit diesen Inhalten
soll ein Problembewusstsein und eine Sensibilisierung einerseits, andererseits ein
Abbau von Hemmungen zur Auseinandersetzung mit Todkranken erreicht werden.
Derartige Ausbildungsprogramme ersetzen jedoch nicht kontinuierliche Formen der
Supervision und Fortbildung, wie sie vor allem in solchen Stationen sinnvoll erscheinen,
die einen hohen Anteil an unheilbar Kranken versorgen. Hierzu zählen insbesondere
Supervisions- und Balint Gruppen. Gemessen an den Kenntnissen über die spezifischen
Bedürfnisse Todkranker und Sterbender und ihrer Bezugspersonen, sind nach wie vor
zahlreiche Defizite in der klinischen Versorgung festzustellen, die zu den Belastungen
der Betroffenen und ihres sozialen Umfeldes beitragen. Neben meist supportiven
psychotherapeutischen Hilfen steht daher die Beratung von Team und Familienangehörigen
im Vordergrund.
More from http://www.universidadazteca.net/study_offers (20)
Video traffic on the Internet is constantly growing; networked multimedia applications consume a predominant share of the available Internet bandwidth. A major technical breakthrough and enabler in multimedia systems research and of industrial networked multimedia services certainly was the HTTP Adaptive Streaming (HAS) technique. This resulted in the standardization of MPEG Dynamic Adaptive Streaming over HTTP (MPEG-DASH) which, together with HTTP Live Streaming (HLS), is widely used for multimedia delivery in today’s networks. Existing challenges in multimedia systems research deal with the trade-off between (i) the ever-increasing content complexity, (ii) various requirements with respect to time (most importantly, latency), and (iii) quality of experience (QoE). Optimizing towards one aspect usually negatively impacts at least one of the other two aspects if not both. This situation sets the stage for our research work in the ATHENA Christian Doppler (CD) Laboratory (Adaptive Streaming over HTTP and Emerging Networked Multimedia Services; https://athena.itec.aau.at/), jointly funded by public sources and industry. In this talk, we will present selected novel approaches and research results of the first year of the ATHENA CD Lab’s operation. We will highlight HAS-related research on (i) multimedia content provisioning (machine learning for video encoding); (ii) multimedia content delivery (support of edge processing and virtualized network functions for video networking); (iii) multimedia content consumption and end-to-end aspects (player-triggered segment retransmissions to improve video playout quality); and (iv) novel QoE investigations (adaptive point cloud streaming). We will also put the work into the context of international multimedia systems research.
GDG Cloud Southlake #34: Neatsun Ziv: Automating AppsecJames Anderson
The lecture titled "Automating AppSec" delves into the critical challenges associated with manual application security (AppSec) processes and outlines strategic approaches for incorporating automation to enhance efficiency, accuracy, and scalability. The lecture is structured to highlight the inherent difficulties in traditional AppSec practices, emphasizing the labor-intensive triage of issues, the complexity of identifying responsible owners for security flaws, and the challenges of implementing security checks within CI/CD pipelines. Furthermore, it provides actionable insights on automating these processes to not only mitigate these pains but also to enable a more proactive and scalable security posture within development cycles.
The Pains of Manual AppSec:
This section will explore the time-consuming and error-prone nature of manually triaging security issues, including the difficulty of prioritizing vulnerabilities based on their actual risk to the organization. It will also discuss the challenges in determining ownership for remediation tasks, a process often complicated by cross-functional teams and microservices architectures. Additionally, the inefficiencies of manual checks within CI/CD gates will be examined, highlighting how they can delay deployments and introduce security risks.
Automating CI/CD Gates:
Here, the focus shifts to the automation of security within the CI/CD pipelines. The lecture will cover methods to seamlessly integrate security tools that automatically scan for vulnerabilities as part of the build process, thereby ensuring that security is a core component of the development lifecycle. Strategies for configuring automated gates that can block or flag builds based on the severity of detected issues will be discussed, ensuring that only secure code progresses through the pipeline.
Triaging Issues with Automation:
This segment addresses how automation can be leveraged to intelligently triage and prioritize security issues. It will cover technologies and methodologies for automatically assessing the context and potential impact of vulnerabilities, facilitating quicker and more accurate decision-making. The use of automated alerting and reporting mechanisms to ensure the right stakeholders are informed in a timely manner will also be discussed.
Identifying Ownership Automatically:
Automating the process of identifying who owns the responsibility for fixing specific security issues is critical for efficient remediation. This part of the lecture will explore tools and practices for mapping vulnerabilities to code owners, leveraging version control and project management tools.
Three Tips to Scale the Shift Left Program:
Finally, the lecture will offer three practical tips for organizations looking to scale their Shift Left security programs. These will include recommendations on fostering a security culture within development teams, employing DevSecOps principles to integrate security throughout the development
UiPath Community Day Kraków: Devs4Devs ConferenceUiPathCommunity
We are honored to launch and host this event for our UiPath Polish Community, with the help of our partners - Proservartner!
We certainly hope we have managed to spike your interest in the subjects to be presented and the incredible networking opportunities at hand, too!
Check out our proposed agenda below 👇👇
08:30 ☕ Welcome coffee (30')
09:00 Opening note/ Intro to UiPath Community (10')
Cristina Vidu, Global Manager, Marketing Community @UiPath
Dawid Kot, Digital Transformation Lead @Proservartner
09:10 Cloud migration - Proservartner & DOVISTA case study (30')
Marcin Drozdowski, Automation CoE Manager @DOVISTA
Pawel Kamiński, RPA developer @DOVISTA
Mikolaj Zielinski, UiPath MVP, Senior Solutions Engineer @Proservartner
09:40 From bottlenecks to breakthroughs: Citizen Development in action (25')
Pawel Poplawski, Director, Improvement and Automation @McCormick & Company
Michał Cieślak, Senior Manager, Automation Programs @McCormick & Company
10:05 Next-level bots: API integration in UiPath Studio (30')
Mikolaj Zielinski, UiPath MVP, Senior Solutions Engineer @Proservartner
10:35 ☕ Coffee Break (15')
10:50 Document Understanding with my RPA Companion (45')
Ewa Gruszka, Enterprise Sales Specialist, AI & ML @UiPath
11:35 Power up your Robots: GenAI and GPT in REFramework (45')
Krzysztof Karaszewski, Global RPA Product Manager
12:20 🍕 Lunch Break (1hr)
13:20 From Concept to Quality: UiPath Test Suite for AI-powered Knowledge Bots (30')
Kamil Miśko, UiPath MVP, Senior RPA Developer @Zurich Insurance
13:50 Communications Mining - focus on AI capabilities (30')
Thomasz Wierzbicki, Business Analyst @Office Samurai
14:20 Polish MVP panel: Insights on MVP award achievements and career profiling
Implementations of Fused Deposition Modeling in real worldEmerging Tech
The presentation showcases the diverse real-world applications of Fused Deposition Modeling (FDM) across multiple industries:
1. **Manufacturing**: FDM is utilized in manufacturing for rapid prototyping, creating custom tools and fixtures, and producing functional end-use parts. Companies leverage its cost-effectiveness and flexibility to streamline production processes.
2. **Medical**: In the medical field, FDM is used to create patient-specific anatomical models, surgical guides, and prosthetics. Its ability to produce precise and biocompatible parts supports advancements in personalized healthcare solutions.
3. **Education**: FDM plays a crucial role in education by enabling students to learn about design and engineering through hands-on 3D printing projects. It promotes innovation and practical skill development in STEM disciplines.
4. **Science**: Researchers use FDM to prototype equipment for scientific experiments, build custom laboratory tools, and create models for visualization and testing purposes. It facilitates rapid iteration and customization in scientific endeavors.
5. **Automotive**: Automotive manufacturers employ FDM for prototyping vehicle components, tooling for assembly lines, and customized parts. It speeds up the design validation process and enhances efficiency in automotive engineering.
6. **Consumer Electronics**: FDM is utilized in consumer electronics for designing and prototyping product enclosures, casings, and internal components. It enables rapid iteration and customization to meet evolving consumer demands.
7. **Robotics**: Robotics engineers leverage FDM to prototype robot parts, create lightweight and durable components, and customize robot designs for specific applications. It supports innovation and optimization in robotic systems.
8. **Aerospace**: In aerospace, FDM is used to manufacture lightweight parts, complex geometries, and prototypes of aircraft components. It contributes to cost reduction, faster production cycles, and weight savings in aerospace engineering.
9. **Architecture**: Architects utilize FDM for creating detailed architectural models, prototypes of building components, and intricate designs. It aids in visualizing concepts, testing structural integrity, and communicating design ideas effectively.
Each industry example demonstrates how FDM enhances innovation, accelerates product development, and addresses specific challenges through advanced manufacturing capabilities.
The Rise of Supernetwork Data Intensive ComputingLarry Smarr
Invited Remote Lecture to SC21
The International Conference for High Performance Computing, Networking, Storage, and Analysis
St. Louis, Missouri
November 18, 2021
How Netflix Builds High Performance Applications at Global ScaleScyllaDB
We all want to build applications that are blazingly fast. We also want to scale them to users all over the world. Can the two happen together? Can users in the slowest of environments also get a fast experience? Learn how we do this at Netflix: how we understand every user's needs and preferences and build high performance applications that work for every user, every time.
How RPA Help in the Transportation and Logistics Industry.pptxSynapseIndia
Revolutionize your transportation processes with our cutting-edge RPA software. Automate repetitive tasks, reduce costs, and enhance efficiency in the logistics sector with our advanced solutions.
INDIAN AIR FORCE FIGHTER PLANES LIST.pdfjackson110191
These fighter aircraft have uses outside of traditional combat situations. They are essential in defending India's territorial integrity, averting dangers, and delivering aid to those in need during natural calamities. Additionally, the IAF improves its interoperability and fortifies international military alliances by working together and conducting joint exercises with other air forces.
Performance Budgets for the Real World by Tammy EvertsScyllaDB
Performance budgets have been around for more than ten years. Over those years, we’ve learned a lot about what works, what doesn’t, and what we need to improve. In this session, Tammy revisits old assumptions about performance budgets and offers some new best practices. Topics include:
• Understanding performance budgets vs. performance goals
• Aligning budgets with user experience
• Pros and cons of Core Web Vitals
• How to stay on top of your budgets to fight regressions
What's Next Web Development Trends to Watch.pdfSeasiaInfotech2
Explore the latest advancements and upcoming innovations in web development with our guide to the trends shaping the future of digital experiences. Read our article today for more information.
Sustainability requires ingenuity and stewardship. Did you know Pigging Solutions pigging systems help you achieve your sustainable manufacturing goals AND provide rapid return on investment.
How? Our systems recover over 99% of product in transfer piping. Recovering trapped product from transfer lines that would otherwise become flush-waste, means you can increase batch yields and eliminate flush waste. From raw materials to finished product, if you can pump it, we can pig it.
Interaction Latency: Square's User-Centric Mobile Performance MetricScyllaDB
Mobile performance metrics often take inspiration from the backend world and measure resource usage (CPU usage, memory usage, etc) and workload durations (how long a piece of code takes to run).
However, mobile apps are used by humans and the app performance directly impacts their experience, so we should primarily track user-centric mobile performance metrics. Following the lead of tech giants, the mobile industry at large is now adopting the tracking of app launch time and smoothness (jank during motion).
At Square, our customers spend most of their time in the app long after it's launched, and they don't scroll much, so app launch time and smoothness aren't critical metrics. What should we track instead?
This talk will introduce you to Interaction Latency, a user-centric mobile performance metric inspired from the Web Vital metric Interaction to Next Paint"" (web.dev/inp). We'll go over why apps need to track this, how to properly implement its tracking (it's tricky!), how to aggregate this metric and what thresholds you should target.
How to Avoid Learning the Linux-Kernel Memory ModelScyllaDB
The Linux-kernel memory model (LKMM) is a powerful tool for developing highly concurrent Linux-kernel code, but it also has a steep learning curve. Wouldn't it be great to get most of LKMM's benefits without the learning curve?
This talk will describe how to do exactly that by using the standard Linux-kernel APIs (locking, reference counting, RCU) along with a simple rules of thumb, thus gaining most of LKMM's power with less learning. And the full LKMM is always there when you need it!
AC Atlassian Coimbatore Session Slides( 22/06/2024)apoorva2579
This is the combined Sessions of ACE Atlassian Coimbatore event happened on 22nd June 2024
The session order is as follows:
1.AI and future of help desk by Rajesh Shanmugam
2. Harnessing the power of GenAI for your business by Siddharth
3. Fallacies of GenAI by Raju Kandaswamy
Fluttercon 2024: Showing that you care about security - OpenSSF Scorecards fo...Chris Swan
Have you noticed the OpenSSF Scorecard badges on the official Dart and Flutter repos? It's Google's way of showing that they care about security. Practices such as pinning dependencies, branch protection, required reviews, continuous integration tests etc. are measured to provide a score and accompanying badge.
You can do the same for your projects, and this presentation will show you how, with an emphasis on the unique challenges that come up when working with Dart and Flutter.
The session will provide a walkthrough of the steps involved in securing a first repository, and then what it takes to repeat that process across an organization with multiple repos. It will also look at the ongoing maintenance involved once scorecards have been implemented, and how aspects of that maintenance can be better automated to minimize toil.
Fluttercon 2024: Showing that you care about security - OpenSSF Scorecards fo...
Mechanism of action of the Body Wave
1. Mechanism of action of the Body Wave
Gerhard Lingg
Interuniversity College for Health and Development Graz / Castle of Seggau, Austria
Bioregulational Background of the Effect of Body-Waves
and Nutrition Advices
Resource management is essential for the practical salute-genesis and the regulation
medicine, as thereby damaged health conditions can be transferred into new processes
by sophisticated means in-between the determinants health and decease.
On the one hand steadily stages of development are available which can differentiate to
health stages. On the other hand there exists increasingly more evidence of decease
patterns of therapy indicating semeiotics in a considerably larger differentiation potential
as initially assumed. Our knowledge about the regulation of health- and decease stages
is incomplete and equipped with barriers.
Transcription factors regulate the expression at the end of signal-transduction-
pathways. The basis of these pathways, and therefore of fundamental relevance for the
communication of micro milieu biology, are interactions. The itemization of these actions
displays the necessary requirement for the differentiation.
It is indeed needful to consult analogs in order to get from linear actions to complex
pattern detections.
An analog out of biology here serves as an introducing example:
Weismann brings into service of agriculture his Barrier-Theory while recommending
one-way-signals for marking diversified bio-seeds. (Black et al. 2006)
As is generally known the most popular theorist of evolution next to Darwin, August
Weismann 1876, describes the development of transmutation (Change Of The Species)
along the way of direct impact of exterior living condition: “Observing each variety as a
reaction of the organism due to exterior impact as a deviation of the inherited
development direction, the reason of this is, that without any change of environment
there could not have occurred any development of organic patterns.
This „Weismann-Barrier” even today is a global basis for the hybrid of several cultivated
forms of crop plants. (Ebert, A.W. et al. 2007)
Only the discovery and interpretation of the „Reverse Transcriptase“ has brought doubts
in the severity of the linear theory. The reverse transcriptase has first been described in
1970 independently from Howard Temin as well as from
David Baltimore. In 1975 they obtained the Nobel Price for their discovery together with
Renato Dulbecco.
The name „reverse“ here describes the special qualities of the enzyme to reverse the
transcription process of DNA to RNA, which previously was seen as the only possible
way. With the discovery of these enzymes the by then current “Dogma of Molecular
Biology”, stating there exists only a one-way communication in the direction DNA →
RNA → protein and never the other way round, has been scrapped.
(Coffin, J.M. et al. 1997)
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES
2. Body-Wave
Another analogue is the operation principle of the Body-Waves and the nutrition
advices. The hypothesis relating to this is based on the studies of Jürgen Schole.
(Schole, J. et al. 1988)
Thus the biological systems go into resonance with substantial-analog information and
over reciprocal action the regulation procedures are getting started.
Cell or nuclear membrane receptors, otherwise undocked by regulators, e.g. agents out
of medicine, perhaps have an adherence- or carrier-function as dipole-structures.
They help at the transmission of information or they are not used anymore, because
electron transport systems in the cell nucleus and cytosol are able to get directly into
resonance with the information. Therefore the electron performance in the membrane
persistant flavin-enzyme system and thereby e.g. the metabolic condition might be
regulated by biological effective information, modulated on electro-magnetic fields.
These receptor adherence action is described in the studies of Schole.
After all its origin can be found in the former molecular biology:
The effect of substrates is after the theory of Paul Ehrlichs bound to receptors, which
have to be built like a cell. A lack of receptors confines the substrates efficacy and
therefore the consequent metabolism.
But this can sometimes cause in a therapeutic sense undesirable side effects, while the
organism gets into resonance with the information of a metabolite.
This would not occur with a suitable bio-physical information transfer.
Metabolic regulations and regulation deceases
By acquired dialectic the human of our culture sphere is primary thinking in dualities. To
assess polarities means to talk about a condition and at the same time consider its
antithesis. Because probably only in the “as-well-as” the truth can be found, to which we
can converge step by step.
Albert Einstein has established, in the course of designating, the nine characteristics of
the human in mathematical concern to his skills, the following dictum:
The human makes his choice basically between three possibilities, even though he
realizes only two of it. Therewith he enables himself to consider an average between
two determinants in order to outbalance extremes.
With this Einstein already is consistent with the newest studies in brain research of the
last century, viewing the reality not as reality but as an image of the highest
sophisticated substance of the human body, the cortex of brain.
(Spranger et al. 2004)
The semantic of regulation biology, its physiology and medicine has its origin in the
human understanding of symptomatology.
The regulation deceases described by Jürgen Schole and his school are using the
semiotic of health and decease, resp. regarding the latter, the nosology, to gain a wider
range of understanding beneath health scientists and physicians.
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES
3. In extension of the former WHO-definition health is not defined as a singular but as
three stages. Which there are counted among the primary, the liberty of damage, the
secondary which means reversibility and the tertiary, the prognosis under influence of a
therapy. Deceases are therefore subdivided into therapy-based classifications of
regulation medicine into ethological-homologues (as in most cases of infection),
pathogenetic hetereologue or cascadical damages showing complex patterns with
individual designs. (Spranger 2007)
Symptoms of decease are showing a hidden imbalance of which we once found should
work out its origin and further eliminate it.
This imbalance can become apparent on three different levels and has to be balanced
there. The decision pattern should be identical with the prime levels of psyche
intervention, metabolism and matter, as well as again 3 determinants.
In this outline it conveys that decease is not anything negative but another experience-
of-live, how Rudolf Virchow phrases. An imbalance manifests decease, he inhibits the
organism on his way to experience health.
Every regularly running acute decease goes along with an immunological action and is
a healing action because it utilizes at the same time reparative and proliferative
tendencies, which can bear down any stress (infect, trauma) in a regulating way.
Only a chronic process contains the problems of metabolic efforts taken in turns to each
other.
Mind-Body-Medicine And Information
„Mind-Body-Medicine focuses on the interactions among the brain, mind,
body, and behavior, and the powerful ways in which emotional, mental,
social, spiritual and behavioural factors can directly affect health. It regards
as fundamental an approach that respects and enhances each person’s
capacity for self-knowledge and self-care, and it emphases techniques that
are grounded in this approach.” Herewith the NIH describes intervention techniques,
which offer the access to cognitive behavioural changes of affected persons.
(NIH 2006)
The principles of mind-body-medicine is the dealing with information and the self-
constitution of life draft and style. (Dobos, G.J. 2007)
The effect of information in living, complex systems is unlikely larger than in technical
equipment. In the organism it can only lead to an effect if the information transfer is
given, which is steadily operated self-regulated. Information characterizes reality
between mass and energy. It is the form shaping power between the determinants.
Matter is not only mass but also energy and information.
Resonance
A vast number of information runs through the organism without causing any reaction.
The possibility that in an individual case our organism is arranged to make a reaction, is
only big, when it comes to resonance.
Indeed a change is only achieved by information which goes into resonance with the
complex biological system.
Basis for this is the compliance, which means the affinity of information to the
resonance system acc. to the principle of sender-receptor-acceptor.
Only then we can anticipate interaction in the biological system leading to regulation.
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES
4. Metabolic-Regulation
In medicine there are slightly known synthetic concepts although they have a scientific
background.
It is a matter of concepts of dynamic regulative systems, which part of them are
standing contrary to the generally inflexible point of views.
The human is a complex system, handling information with a dynamic order, which
points out polarities. The organism succeeds in dynamically combining the opposites of
a determined chaos and order.
The concept of metabolic regulation could show, which method is better suitable to help
a patient finding his health target in an individual and optimal way.
The method itself doesn’t play a role, indeed a proof of efficacy should be possible.
The metabolic regulation can achieve the following (Schole, J et al., 1988):
With the measurement of metabolic regulation we are holding in our hands an
instrument, which enables us to certify the efficacy of a therapy process directly at the
patient in a very individual way.
Only the positive influence of a deadlocked metabolic condition of an ill patient shows,
that the chosen method is suitable for him. The metabolic regulation forms a reference
platform between environmental influence, nutrition, mind and therapy out of all medical
fields.
The anabolic synthesis and the catabolic energy metabolism are linked with and depend
on each other as a polarity. Non of both can be described without contemporary
consideration of its partner (Yin-Yang-Principle). In a state of rest the metabolic action is
the same. It is guaranteed by the so-called basis regulation, which
is marked with oxidation- and reduction-processes.
Through the exchange of electrons over persistant flavin-enzymes in the nucleus,
cytosol and mitochondria following the principle of electron-donator-acceptor-reaction a
steadily give-and-take is happening.
The redox potential defines the basis regulation and therefore guarantees the regular
metabolism, the cell’s “daily-routine-metabolism”. Schole writes: “Synthesizing on the
pasteur-effect as the most elementary regulation principle all experimental facts and all
evidence pleads for the basis regulation in all cells of a higher organism taking place
over the redox-potential. This is to be completed by the possibility of interconversion
and allostery.
‚Second-Messenger-Systems’ are not only used for basis regulation but also for very
fast regulations as for example in special regulatory circuits, whereby the whole
regulation system experiences a tight connection.
Basis regulation happens by three-component-systems:
Corticoids and thyroid hormones regulate as catabolic components the energy
metabolism in the mitochondria and in the nucleus and by Somatotropin provided
peptides as anabolic components they regulate the synthesis metabolism in the area of
Cytosol and nucleus. These are the three main metabolic hormones of endocrinium.
A second system, connected thightly with the endocrinium and used for the basic
regulation modulation, consist of Noradrenalin as catabolic and of Acetylcholine as
anabolic components of the vegetativum.
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES
5. To guarantee an optimal and sufficient solid stationary condition between energy- and
synthesis-metabolism and therefore an ideal redox-status for the several cell
compartments, the components of both systems have to be available inside the cells in
an optimal relation to each other and in sufficient quantity
An optimal solid metabolic condition corresponds to the idea of “Health“.
During a positive stress adaptation the main metabolic hormones are provided by the
depots within one hour, under high significant increase of the organism’s functionality.
During a long-term stress situation under participation of the nucleus an adaption of
enzyme patterns, quantity of mitochondria, etc. accordingly to the new situation
happens. When one component is provided preferentially this leads to a regulative
lapse, which became apparent as regulation deceases.
A negative stress adaptation corresponds therefore to the idea of “chronic decease”.
The knowledge of concentration and with this the efficiency of both endocrine and both
vegetative components in the organism is therefore, in the medical diagnostic, the
therapy or prophylaxes of exceptional meaning.
Acute deceases only occur if the Cortisol storage resp. anabolic peptides are exhausted
because of stress. Since then a stress adaptation after an immediate reaction within
one hour is not possible anymore.
In this case it comes to an alarm reaction, which can last 7 days and has to be
understood as healing reaction (Adaption-Syndrome).
Here the production of anabolic peptides on the one hand and of Cortisol on the other
hand hast o be increased, before the metabolic condition can be optimally adjusted.
The two phases not only differentiate in time, but also in various activities of metabolic
stages at the beginning. In the quicker phase it primary comes to an increased catabolic
activity, which means sympathicotonia and in the slower phase it primary comes to an
increased anabolic activity, which means parasympathiconia.
Example: During a shock as primary anabolic reaction with all welI-known inflammatory-
signs a lack of catabolic activity exists. So catabolic effective corticoid is given!
An optimal-solid metabolic condition with undisturbed information transfer would be able
to equate to the idea of “Health”.
Metabolic Lapse
Every chronic decease develops through a regulative disharmony, through a metabolic
lapse within the cells. All deceases are divided into anabolic and catabolic because of
their symptomatic. The origin however is in each case the malfunction of polar
metabolic activities of energy- or synthesis-metabolism. The underlain blocking has to
be always diagnostically recorded and specifically treated. It can be situated on all
levels of being, from mind to matrix.
Therefore every chronic decease has to be primary studied onto the fact how the
normal metabolic condition has been disturbed. So a symptomatical therapy can be
precluded.
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES
6. An example for catabolic metabolic lapses are our civilization deceases. As essential
origin we can ascertain: lack of movement, permanent psychichal stress, carbohydrate
abuse and destruction of lipoproteids (entropy).
The consequence is a catabolism, affection of the heart-circulation-system as well as
degenerative deceases.
The stressed human is only increasingly vulnerable for infects, because his anabolic
metabolic power is blocked. STH is the strongest immune stimulating, anabolic-effective
hormone. In case of a lack of STH, often additionally blocked through too much insulin
(carbohydrate abuse), the catabolism predominates.
During the post-aggression-syndrome after surgeries, trauma or infections there is also
extreme catabolism.
Reciprocal there is an acute anabolism at a shock due to extreme blockings of catabolic
metabolic power. In order to balance the deficient catabolic polarity, in this case we
have to administer catabolic-effective Cortisol.
Metabolic Therapy
Negative stress adaptations require chronic deceases as consequence of a cellular
regulation disturbance. A healthy person with a dynamical metabolism can easily
balance anabolic or catabolic lapses. The chronically sick person although remains in a
frozen regulation of its metabolic lapse, which has been caused by the lack of anabolic
or catabolic amount.
The therapy has to begin in the manner of balancing the responsible lack by
empowering the weakest part after the polar principle. The metabolic therapy is an
essential part of biophysical information therapy. During a catabolic metabolic lapse
there should be supplied anabolic metabolic information habitually from the outside
and the other way round, whereas after analyzing the dosage and frequency of taking
has to be fixed. The application should be combined with our nutrition advices referred
to the metabolism.
anabolic
lapse
anabolic
catabolic
lapse
catabolic
optimum
health
anabolic
lapse
anabolic
catabolic
lapse
catabolic
optimum
health
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES
7. hypoergical
anabolic
hypoergical
catabolicBasis Regulation
Radical
development
(ERS, nucleus)
synthesis-SW energy-SW
Thyroxine, Cortisol STH, anabolic peptides
catabolic anabolic
stress
carbohydrates
cellular stress
(release of peptides)
Involution
lymphatic
organs
catabolic
lapse
psycho-stress (STH
is replaced by Insulin,
peptide synthesis)
carbohydrate abuse
Unstable regulation balance
= metabolic condition=
shock
anabolic
lapse
cell-specific
peptides (anabolic)
hypoergical
anabolic
hypoergical
catabolicBasis Regulation
Radical
development
(ERS, nucleus)
synthesis-SW energy-SW
Thyroxine, Cortisol STH, anabolic peptides
catabolic anabolic
stress
carbohydrates
cellular stress
(release of peptides)
Involution
lymphatic
organs
catabolic
lapse
psycho-stress (STH
is replaced by Insulin,
peptide synthesis)
carbohydrate abuse
Unstable regulation balance
= metabolic condition=
shock
anabolic
lapse
cell-specific
peptides (anabolic)
membran-
permeability
oedema,
redness,
swelling
Positive Stress Adaptation
anabolic anabolic katabolic katabolic
membran-
permeability
cell division
differenciation
chronic inflammation
catabolic
blocked
anabolic lapse
catabolic blocking
- psychic inhibition of CHR
- beta- or ganglionic blockers
- inhabitation of electron flow
- insufficiency of NNR or
thyroidea
- dysbiosis (damaged flora by
antibiotics)
catabolic lapse
anabolic blocking
- psychic inhibition of GHRH
- alpha-blockers
- permanent stress (interfering
fields)
- lack of reduced milieu
- carbohydrate abuse (Insulin
blocks STH)
optimal irritant response
=stress respornse
anabolic
blocked
Cytosol mitochon
dria
membran-
permeability
oedema,
redness,
swelling
Positive Stress Adaptation
anabolic anabolic katabolic katabolic
membran-
permeability
cell division
differenciation
chronic inflammation
catabolic
blocked
anabolic lapse
catabolic blocking
- psychic inhibition of CHR
- beta- or ganglionic blockers
- inhabitation of electron flow
- insufficiency of NNR or
thyroidea
- dysbiosis (damaged flora by
antibiotics)
catabolic lapse
anabolic blocking
- psychic inhibition of GHRH
- alpha-blockers
- permanent stress (interfering
fields)
- lack of reduced milieu
- carbohydrate abuse (Insulin
blocks STH)
optimal irritant response
=stress respornse
anabolic
blocked
Cytosol mitochon
dria
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES
8. Conclusion
Acute deceases develop habitually in case of accidents, infections, neglects of various
kinds until finally inflammations of deceases, which are assigned to a chronic
happening. They require medical competence and professional healing assistance.
Every chronic decease develops trough a regulation disharmony, a metabolic lapse
within the cells and within the regulative and managing basic system. (Heine 2007)
Non-linear interaction is sensitive against a number of influences because of its reaction
turns. Therefore an intervention, which proceeds on the variable individual basic
requirements during the analysis as well as in the therapy, operates without a
distribution principle. The target of perception lays in the description, as before
mentioned in the specification of Health and Decease.
All chronic deceases are divided into anabolic and catabolic due to its symptomatic after
Schole. The origin however is in each case the fail of polar activities of determinants of
the energy- or synthesis metabolism.
Therefore the basic blockades have to be captured and further specifically treated.
It can be situated on all levels of being, from the mind to the basic system of the body.
Thus every chronic decease has to be primary analyzed on the reason of the
disharmony in the normal metabolic regulation. The deficit finally defines the leading
symptoms.
This conclusion primary eliminates the principle of a symptomatic therapy of chronic
deceases.
An example for catabolic metabolic lapse are our civilisation deceases. As essential
origins lack of movement, permanent psychic stress, carbohydrate-abuse and the
destruction of lipoproteides (entropy) are considered.
The consequence is a catabolism, are deceases of the heart-circulation-system as well
as degenerative deceases. The stressed human is only vulnerable for infects because
of his metabolic power is blocked.
STH (growth hormone) is the strongest immune-stimulating, anabolic effective hormone
we know. In case of a lack of STH, often additionally blocked by too much insulin,
catabolism predominates.
It is to explain, where the deficit concerning the blockades of the basic system is
situated and where conditions of energy lack can be found, which disturb the metabolic
regulation.
Only therapeutic balance of the deficit creates an optimal solid metabolic condition in an
undisturbed information transfer in the basic system of the organism.
Thus it is detectable, that regulation deceases in typical form can be recovered in nearly
all occasions of chronification.
The purpose of regulation medicine is sophisticated, but enough exemplary to handle
with it.
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES
9. List of literature
1.Black, M., Bewley, J.D., Halmer, P. (2006): The encyclopedia of seedscience,
technology and uses. Cromwell Press, Trowbridge, UK. p. 828
2.Ebert, A.W., Astorga, C., Ebert, I., Mora, A. & C. Umana (2007):
Asegurando Nuetro Futuro. Colecciones de Germoplasma del CATIE. Série
Técnica Bolétin Técnico No. 26. Centro Agronómico Tropical de Investigatión
y Ensenianca Turrialba, Costa Rica. ISBN 978-9977-57-433-2.
3.Coffin, J.M., Hughes, St.H., H.E. Varmus (1997): The Place of Retroviruses
in Biology. Retroviruses Cold Spring Harbor Laboratory Press. ISBN: 0-
07869-571-4.
4.Schole, J. und W. Lutz (1988): Regulationskrankheiten – Versuch einer
fächerübergreifenden Analyse. ISBN: 3-43297-141-9.
5.Spranger, H.: Mind-Body. Separatum zu Spranger, H. & EU-team:
Regulationsbiologische Grundlagen. Modul inter-uni.net. ISBN: 3-9502-326-
0-8.
6.Spranger, H.(Hsgb.): Das Medizinische Gesundheitsdesign. CO’MED
(2007). ISBN 3-934672-21-5. pp. 11-13.
7.National Center for Complementary and Alternative Medicine. Zugriff
12.01.2006 http://nccam.nih.gov/health/mindbody.htm
8.Dobos, G.J., A. Paul (2007): Was ist Mind-Body Medicine. Komplement.
Integrat. Med. 48; Heft 9: 19-24.
9.Heine, H.(2007): Lehrbuch der biologischen Medizin. Grundregulation und
Extrazelluläre Matrix. Hippokrates. ISBN: 3-8304-5335-3.
IMI HEALTH TECHNOLOGIES
IMI HEALTH TECHNOLOGIES