Most relevant results28 results in the last year.
Cost-effectiveness of physical activity interventions for prevention and management of cognitive decline and dementia—a systematic review
Background Although increasing physical activity (PA) has been suggested to
prevent and manage cognitive decline and dementia, its economic impact on
healthcare systems and society is largely unknown. This study aimed to summarize …
prevent and manage cognitive decline and dementia, its economic impact on
healthcare systems and society is largely unknown. This study aimed to summarize …
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor
Ca2+/calmodulin-dependent protein kinase II (CaMKII) hyperactivity causes cardiac
arrhythmias, a major source of morbidity and mortality worldwide. Despite proven
benefits of CaMKII inhibition in numerous preclinical models of heart disease …
arrhythmias, a major source of morbidity and mortality worldwide. Despite proven
benefits of CaMKII inhibition in numerous preclinical models of heart disease …
SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity
SynGAP is an abundant synaptic GTPase-activating protein (GAP) critical for
synaptic plasticity, learning, memory, and cognition. Mutations in SYNGAP1 in
humans result in intellectual disability, autistic-like behaviors, and epilepsy …
synaptic plasticity, learning, memory, and cognition. Mutations in SYNGAP1 in
humans result in intellectual disability, autistic-like behaviors, and epilepsy …
Zebrafish spop promotes ubiquitination and degradation of mavs to suppress antiviral response via the lysosomal pathway
Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) signaling pathways are
required to be tightly controlled to initiate host innate immune responses. Fish
mitochondrial antiviral signaling (mavs) is a key determinant in the RLR pathway …
required to be tightly controlled to initiate host innate immune responses. Fish
mitochondrial antiviral signaling (mavs) is a key determinant in the RLR pathway …
Depression in Individuals With Diabetic Retinopathy in the US National Health and Nutrition Examination Survey, 2005-2008
PURPOSE To examine the relationship between diabetic retinopathy (DR) and
depression in the United States. DESIGN Retrospective, cross-sectional study.
METHODS National Health and Nutrition Examination Survey (NHANES) …
depression in the United States. DESIGN Retrospective, cross-sectional study.
METHODS National Health and Nutrition Examination Survey (NHANES) …
Facilitating youth diabetes studies with the most comprehensive epidemiological dataset available through a public web portal
The prevalence of type 2 diabetes mellitus (DM) and prediabetes (preDM) is rapidly
increasing among youth, posing significant health and economic consequences. To
address this growing concern, we created the most comprehensive youth-focused …
increasing among youth, posing significant health and economic consequences. To
address this growing concern, we created the most comprehensive youth-focused …
Association Between Serum Vitamin D Levels and Myopia in the National Health and Nutrition Examination Survey (2001–2006)
Purpose To assess the relationship between serum vitamin D levels and myopia in
people aged 12–50 years using the National Health and Nutrition Examination
Survey (NHANES) database. Methods Demographics, vision, and serum vitamin D …
people aged 12–50 years using the National Health and Nutrition Examination
Survey (NHANES) database. Methods Demographics, vision, and serum vitamin D …
Variation in Home Healthcare Use by Dementia Status Among a National Cohort of Older Adults
Background Medicare-funded home healthcare (HHC) delivers skilled nursing,
therapy, and related services through visits to the patient's home. Nearly one-third
(31%) of HHC patients have diagnosed dementia, but little is currently known …
therapy, and related services through visits to the patient's home. Nearly one-third
(31%) of HHC patients have diagnosed dementia, but little is currently known …
Analysis of brain structural covariance network in Cushing disease
Background Cushing disease (CD) is a rare clinical neuroendocrine disease. CD is
characterized by abnormal hypercortisolism induced by a pituitary adenoma with the
secretion of adrenocorticotropic hormone. Individuals with CD usually exhibit atrophy …
characterized by abnormal hypercortisolism induced by a pituitary adenoma with the
secretion of adrenocorticotropic hormone. Individuals with CD usually exhibit atrophy …
County-Level Social Vulnerability, Metropolitan Status, and Availability of Home Health Services
Home-based medical care (HBMC) and skilled home health care (HHC) are key
components of clinical care for the growing population of homebound older adults in
the US. 1, 2 We examined differences in HBMC clinicians and skilled HHC agencies …
components of clinical care for the growing population of homebound older adults in
the US. 1, 2 We examined differences in HBMC clinicians and skilled HHC agencies …
No less relevant results in the last month.