Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke
Y Xia, X Ling, G Hu, Q Zhu, J Zhang, Q Li… - Stem cell research & …, 2020 - Springer
Background Small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSC)
derived from human induced pluripotent stem cells (iPSC, iMSC-sEV) are considered to …
derived from human induced pluripotent stem cells (iPSC, iMSC-sEV) are considered to …
Application of mesenchymal stem cell-derived extracellular vesicles for stroke: biodistribution and microRNA study
GJ Moon, JH Sung, DH Kim, EH Kim, YH Cho… - Translational stroke …, 2019 - Springer
Mesenchymal stem cells (MSCs) exert their therapeutic capability through a variety of
bioactive substances, including trophic factors, microRNAs, and extracellular vesicles (EVs) …
bioactive substances, including trophic factors, microRNAs, and extracellular vesicles (EVs) …
Exosomes derived from bone marrow mesenchymal stem cells promote angiogenesis in ischemic stroke mice via upregulation of MiR-21-5p
H Hu, X Hu, L Li, Y Fang, Y Yang, J Gu, J Xu, L Chu - Biomolecules, 2022 - mdpi.com
Exosomes derived from bone mesenchymal stem cells (BMSC-Exos) are one of the main
factors responsible for the therapeutic effects of BMSCs. The study aimed to investigate …
factors responsible for the therapeutic effects of BMSCs. The study aimed to investigate …
Embryonic stem cell derived small extracellular vesicles modulate regulatory T cells to protect against ischemic stroke
Y Xia, G Hu, Y Chen, J Yuan, J Zhang, S Wang, Q Li… - ACS …, 2021 - ACS Publications
Stem cell derived small extracellular vesicles (sEVs) have been proved to promote
neurological recovery after stroke. Recent studies demonstrate a phenomenal tissue repair …
neurological recovery after stroke. Recent studies demonstrate a phenomenal tissue repair …
In vivo monitoring and assessment of exogenous mesenchymal stem cell-derived exosomes in mice with ischemic stroke by molecular imaging
R Xu, Y Bai, S Min, X Xu, T Tang… - International Journal of …, 2020 - Taylor & Francis
Purpose Mesenchymal stem cell-derived exosomes (MSC-exos) are considered an
important restorative treatment for ischemic stroke. However, the migration ability and …
important restorative treatment for ischemic stroke. However, the migration ability and …
Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats
H Xin, Y Li, Y Cui, JJ Yang… - Journal of Cerebral …, 2013 - journals.sagepub.com
Here, for the first time, we test a novel hypothesis that systemic treatment of stroke with
exosomes derived from multipotent mesenchymal stromal cells (MSCs) promote …
exosomes derived from multipotent mesenchymal stromal cells (MSCs) promote …
Mesenchymal stromal cell-derived small extracellular vesicles promote neurological recovery and brain remodeling after distal middle cerebral artery occlusion in …
DA Dumbrava, R Surugiu, V Börger, M Ruscu, T Tertel… - Geroscience, 2022 - Springer
Small extracellular vesicles (sEVs) obtained from mesenchymal stromal cells (MSCs)
promote neurological recovery after middle cerebral artery occlusion (MCAO) in young …
promote neurological recovery after middle cerebral artery occlusion (MCAO) in young …
Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and …
J Gregorius, C Wang, O Stambouli, T Hussner… - Basic research in …, 2021 - Springer
Obtained from the right cell-type, mesenchymal stromal cell (MSC)-derived small
extracellular vesicles (sEVs) promote stroke recovery. Within this process, microvascular …
extracellular vesicles (sEVs) promote stroke recovery. Within this process, microvascular …
[HTML][HTML] MSC-derived exosomes can enhance the angiogenesis of human brain MECs and show therapeutic potential in a mouse model of Parkinson's disease
C Xue, X Li, L Ba, M Zhang, Y Yang, Y Gao… - Aging and …, 2021 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is the second most widespread neurodegenerative disorder in the
world. It has been reported that exosomes derived from mesenchymal stem cells (MSCs) …
world. It has been reported that exosomes derived from mesenchymal stem cells (MSCs) …
Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood–brain barrier disruption in murine ischemic stroke models
L Qiu, Y Cai, Y Geng, X Yao, L Wang, H Cao, X Zhang… - Acta Biomaterialia, 2022 - Elsevier
Intracerebral hemorrhage following blood–brain barrier (BBB) disruption resulting from
thrombolysis of ischemic stroke with tissue plasminogen activator (tPA) remains a critical …
thrombolysis of ischemic stroke with tissue plasminogen activator (tPA) remains a critical …