Mitochondria as a therapeutic target for ischemic stroke
Z He, N Ning, Q Zhou, SE Khoshnam… - Free Radical Biology and …, 2020 - Elsevier
Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …
[HTML][HTML] Mitochondria in ischemic stroke: new insight and implications
F Liu, J Lu, A Manaenko, J Tang, Q Hu - Aging and disease, 2018 - ncbi.nlm.nih.gov
Stroke is the leading cause of death and adult disability worldwide. Mitochondrial
dysfunction has been regarded as one of the hallmarks of ischemia/reperfusion (I/R) …
dysfunction has been regarded as one of the hallmarks of ischemia/reperfusion (I/R) …
Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
P Wang, Y Cui, Q Ren, B Yan, Y Zhao, P Yu… - Cell death & …, 2021 - nature.com
Ischaemic stroke is becoming the most common cerebral disease in aging populations, but
the underlying molecular mechanism of the disease has not yet been fully elucidated …
the underlying molecular mechanism of the disease has not yet been fully elucidated …
Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice
Y Wang, M Tian, J Tan, X Pei, C Lu, Y Xin… - Journal of …, 2022 - Springer
Background Neuroinflammation is a crucial factor in the development of secondary brain
injury after intracerebral hemorrhage (ICH). Irisin is a newly identified myokine that confers …
injury after intracerebral hemorrhage (ICH). Irisin is a newly identified myokine that confers …
[HTML][HTML] Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function
Y Lai, P Lin, M Chen, Y Zhang, J Chen, M Zheng, J Liu… - Redox Biology, 2020 - Elsevier
Background Ischemic stroke can induce changes in mitochondrial morphology and function.
As a regulatory gene in mitochondria, optic atrophy 1 (OPA1) plays a pivotal role in the …
As a regulatory gene in mitochondria, optic atrophy 1 (OPA1) plays a pivotal role in the …
Relevant mediators involved in and therapies targeting the inflammatory response induced by activation of the NLRP3 inflammasome in ischemic stroke
Q Xu, B Zhao, Y Ye, Y Li, Y Zhang, X Xiong… - Journal of …, 2021 - Springer
The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin
domain-containing 3 (NLRP3) inflammasome is a member of the NLR family of inherent …
domain-containing 3 (NLRP3) inflammasome is a member of the NLR family of inherent …
[HTML][HTML] The role of mitochondrial dynamics in cerebral ischemia-reperfusion injury
J Huang, L Chen, Z Yao, X Sun, X Tong… - Biomedicine & …, 2023 - Elsevier
Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …
Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation
L Yang, H Youngblood, C Wu, Q Zhang - Translational neurodegeneration, 2020 - Springer
Mitochondrial dysfunction plays a central role in the formation of neuroinflammation and
oxidative stress, which are important factors contributing to the development of brain …
oxidative stress, which are important factors contributing to the development of brain …
Mitochondrial transplantation attenuates cerebral ischemia‐reperfusion injury: possible involvement of mitochondrial component separation
Q Xie, J Zeng, Y Zheng, T Li, J Ren… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. Mitochondrial dysfunctions play a pivotal role in cerebral ischemia‐reperfusion
(I/R) injury. Although mitochondrial transplantation has been recently explored for the …
(I/R) injury. Although mitochondrial transplantation has been recently explored for the …
miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathway
Y Li, J Wang, S Chen, P Wu, S Xu, C Wang… - Stem Cell Research & …, 2020 - Springer
Background We have previously verified the beneficial effects of exosomes from endothelial
progenitor cells (EPC-EXs) in ischemic stroke. However, the effects of EPC-EXs in …
progenitor cells (EPC-EXs) in ischemic stroke. However, the effects of EPC-EXs in …