Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …

Deficiency in vitamin D (VitD), a lipid-soluble vitamin and steroid hormone, affects
approximately 24% to 40% of the population of the Western world. In addition to its well …

Despite advances in acute management and prevention of cerebrovascular disease, stroke
and vascular cognitive impairment together remain the world's leading cause of death and …

The incidence of age-related dementia is increasing as the world population ages and due
to lack of effective treatments for dementia. Vascular contributions to cognitive impairment …

Blood pressure (BP) elevations often complicate the management of intracerebral
hemorrhage and aneurysmal subarachnoid hemorrhage, the most serious forms of acute …

Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …

The cerebral circulation responds differently to increases in mean arterial pressure (MAP),
compared to reductions in MAP. We tested the hypothesis that this directional sensitivity is …

High-intensity interval training (HIIE) may present unique challenges to the cerebrovascular
system in individuals post-stroke. We hypothesized lower middle cerebral artery blood …

Directional sensitivity, the more efficient response of cerebral autoregulation to increases,
compared to decreases, in mean arterial pressure (MAP), has been demonstrated with …

The goal of reperfusion therapy for acute ischemic stroke (AIS) is to restore cerebral blood
flow through recanalization of the occluded vessel. Unfortunately, successful recanalization …