Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke

P Jolugbo, RAS Ariëns - Stroke, 2021 - Am Heart Assoc
Thrombi retrieved from patients with acute ischemic stroke are highly heterogeneous.
Recent data suggest that thrombus composition may impact on mechanical thrombectomy …

Cell death pathways in ischemic stroke and targeted pharmacotherapy

A Datta, D Sarmah, L Mounica, H Kaur… - Translational stroke …, 2020 - Springer
Ischemic stroke is one of the significant causes of morbidity and mortality, affecting millions
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …

[HTML][HTML] Structural analysis of ischemic stroke thrombi: histological indications for therapy resistance

S Staessens, F Denorme, O Francois, L Desender… - …, 2020 - ncbi.nlm.nih.gov
Ischemic stroke is caused by a thromboembolic occlusion of cerebral arteries. Treatment is
focused on fast and efficient removal of the occluding thrombus, either via intravenous …

Association of time from stroke onset to groin puncture with quality of reperfusion after mechanical thrombectomy: a meta-analysis of individual patient data from 7 …

R Bourcier, M Goyal, DS Liebeskind, KW Muir… - JAMA …, 2019 - jamanetwork.com
Importance Reperfusion is a key factor for clinical outcome in patients with acute ischemic
stroke (AIS) treated with endovascular thrombectomy (EVT) for large-vessel intracranial …

Outcomes of endovascular treatment for acute intracranial atherosclerosis–related large vessel occlusion

JH Baek, BM Kim, JH Heo, DJ Kim, HS Nam, YD Kim - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Endovascular treatment for acute intracranial atherosclerosis–
related large vessel occlusion (ICAS [+]-LVO) is one of the challenging issues in modern …

Rescue stenting for failed mechanical thrombectomy in acute ischemic stroke: a multicenter experience

Y Chang, BM Kim, OY Bang, JH Baek, JH Heo… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Effective rescue treatment has not yet been suggested in
patients with mechanical thrombectomy (MT) failure. This study aimed to test whether rescue …

Brain functional reserve in the context of neuroplasticity after stroke

J Dąbrowski, A Czajka, J Zielińska-Turek… - Neural …, 2019 - Wiley Online Library
Stroke is the second cause of death and more importantly first cause of disability in people
over 40 years of age. Current therapeutic management of ischemic stroke does not provide …

Per-pass analysis of thrombus composition in patients with acute ischemic stroke undergoing mechanical thrombectomy

S Duffy, R McCarthy, M Farrell, S Thomas, P Brennan… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Mechanical thrombectomy may involve multiple attempts to
retrieve the occluding thrombus. This study examined the composition of thrombus …

Mechanical characterization of thrombi retrieved with endovascular thrombectomy in patients with acute ischemic stroke

N Boodt, PRW Snouckaert van Schauburg, HM Hund… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Mechanical properties of thromboemboli play an important role in
the efficacy of endovascular thrombectomy (EVT) for acute ischemic stroke. However, very …

Blood clot fracture properties are dependent on red blood cell and fibrin content

B Fereidoonnezhad, A Dwivedi, S Johnson… - Acta Biomaterialia, 2021 - Elsevier
Thrombus fragmentation during endovascular stroke treatment, such as mechanical
thrombectomy, leads to downstream emboli, resulting in poor clinical outcomes. Clinical …