Neuroprotective and neurorestorative therapy represent two major drug intervention
strategies for ischemic stroke. Multiple factors such as excitotoxicity, inflammation …

Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

Background Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and a
common cause of end-stage renal disease (ESRD). Mesenchymal stem cells (MSCs) …

Aims We previously showed that the protective effects of endothelial progenitor cells (EPCs)‐
released exosomes (EPC‐EXs) on endothelium in diabetes. However, whether EPC‐EXs …

Electrospinning is a promising method for the rapid and cost-effective production of
nanofibers from a wide variety of polymers given the high surface area morphology of these …

Background Ischemic stroke is a severe neurological disorder that affected millions of
people worldwide. Neuro-inflammation and apoptosis play an essential role in the …

Background: Baicalin (BCL), a candidate drug for ischemic stroke, has been indicated to
protect neurons by promoting brain-derived neurotrophic factor (BDNF). However, the …

Stroke remains the number one cause of morbidity in the United States. Within weeks to
months after an ischemic event, there is a resolution of inflammation and evidence of …

Stroke consists of an abrupt reduction of cerebral blood flow resulting in hypoxia that triggers
an excitotoxicity, oxidative stress, and neuroinflammation. After the ischemic process, neural …

Increasing studies have indicated that abnormal expressed long noncoding RNAs
(lncRNAs) play a vital role in ischemic stroke. Small nucleolar RNA host gene 8 (Snhg8), a …