The role of dietary coconut for the prevention and treatment of Alzheimer's disease: potential mechanisms of action
WMADB Fernando, IJ Martins, KG Goozee… - British Journal of …, 2015 - cambridge.org
Coconut, Cocos nucifera L., is a tree that is cultivated to provide a large number of products,
although it is mainly grown for its nutritional and medicinal values. Coconut oil, derived from …
although it is mainly grown for its nutritional and medicinal values. Coconut oil, derived from …
2014 Update of the Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception
MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2015 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of …
disease (AD), starting decades before dementia onset. Estimates of the prevalence of …
Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings
CR Jack Jr, HJ Wiste, SD Weigand, DS Knopman… - Brain, 2015 - academic.oup.com
We recently demonstrated that the frequencies of biomarker groups defined by the presence
or absence of both amyloidosis (A+) and neurodegeneration (N+) changed dramatically by …
or absence of both amyloidosis (A+) and neurodegeneration (N+) changed dramatically by …
Subjective cognitive concerns, amyloid-β, and neurodegeneration in clinically normal elderly
RE Amariglio, EC Mormino, AC Pietras, GA Marshall… - Neurology, 2015 - AAN Enterprises
Objective: To determine whether neuroimaging biomarkers of amyloid-β (Aβ) and
neurodegeneration (ND) are associated with greater self-reported subjective cognitive …
neurodegeneration (ND) are associated with greater self-reported subjective cognitive …
GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP
Brain amyloid deposition is thought to be a seminal event in Alzheimer's disease. To identify
genes influencing Alzheimer's disease pathogenesis, we performed a genome-wide …
genes influencing Alzheimer's disease pathogenesis, we performed a genome-wide …
[HTML][HTML] Basal forebrain atrophy correlates with amyloid β burden in Alzheimer's disease
The brains of patients suffering from Alzheimer's disease (AD) have three classical
pathological hallmarks: amyloid-beta (Aβ) plaques, tau tangles, and neurodegeneration …
pathological hallmarks: amyloid-beta (Aβ) plaques, tau tangles, and neurodegeneration …
[HTML][HTML] Altered whole-brain white matter networks in preclinical Alzheimer's disease
FU Fischer, D Wolf, A Scheurich, A Fellgiebel… - NeuroImage …, 2015 - Elsevier
Surrogates of whole-brain white matter (WM) networks reconstructed using diffusion tensor
imaging (DTI) are novel markers of structural brain connectivity. Global connectivity of …
imaging (DTI) are novel markers of structural brain connectivity. Global connectivity of …
[HTML][HTML] Metabolic alterations associated to brain dysfunction in diabetes
JMN Duarte - Aging and disease, 2015 - ncbi.nlm.nih.gov
From epidemiological studies it is known that diabetes patients display increased risk of
developing dementia. Moreover, cognitive impairment and Alzheimer's disease (AD) are …
developing dementia. Moreover, cognitive impairment and Alzheimer's disease (AD) are …
The apathy evaluation scale: a comparison of subject, informant, and clinician report in cognitively normal elderly and mild cognitive impairment
BJ Guercio, NJ Donovan, CE Munro… - Journal of …, 2015 - content.iospress.com
Background: Apathy is a common neuropsychiatric symptom in Alzheimer's disease (AD)
dementia and mild cognitive impairment (MCI). Detecting apathy accurately may facilitate …
dementia and mild cognitive impairment (MCI). Detecting apathy accurately may facilitate …