Extending thrombolysis to 4· 5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

BCV Campbell, H Ma, PA Ringleb, MW Parsons… - The Lancet, 2019 - thelancet.com
Background Stroke thrombolysis with alteplase is currently recommended 0–4· 5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …

Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a …

BCV Campbell, CBLM Majoie, GW Albers… - The Lancet …, 2019 - thelancet.com
Background CT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection
for endovascular thrombectomy. We aimed to establish whether imaging assessments of …

Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke

H Ma, BCV Campbell, MW Parsons… - … England Journal of …, 2019 - Mass Medical Soc
Background The time to initiate intravenous thrombolysis for acute ischemic stroke is
generally limited to within 4.5 hours after the onset of symptoms. Some trials have suggested …

MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study

MG Lansberg, M Straka, S Kemp, M Mlynash… - The Lancet …, 2012 - thelancet.com
Background Whether endovascular stroke treatment improves clinical outcomes is unclear
because of the paucity of data from randomised placebo-controlled trials. We aimed to …

ISLES 2015-A public evaluation benchmark for ischemic stroke lesion segmentation from multispectral MRI

O Maier, BH Menze, J Von der Gablentz, L Häni… - Medical image …, 2017 - Elsevier
Ischemic stroke is the most common cerebrovascular disease, and its diagnosis, treatment,
and study relies on non-invasive imaging. Algorithms for stroke lesion segmentation from …

Prediction of tissue outcome and assessment of treatment effect in acute ischemic stroke using deep learning

A Nielsen, MB Hansen, A Tietze, K Mouridsen - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Treatment options for patients with acute ischemic stroke
depend on the volume of salvageable tissue. This volume assessment is currently based on …

Brain ischemia: CT and MRI techniques in acute ischemic stroke

P Vilela, HA Rowley - European journal of radiology, 2017 - Elsevier
Imaging plays a central role for intravenous and intra-arterial arterial ischemic stroke
treatment patient selection. Computed tomography (CT)/CT angiography or magnetic …

Use of deep learning to predict final ischemic stroke lesions from initial magnetic resonance imaging

Y Yu, Y Xie, T Thamm, E Gong, J Ouyang… - JAMA network …, 2020 - jamanetwork.com
Importance Predicting infarct size and location is important for decision-making and
prognosis in patients with acute stroke. Objectives To determine whether a deep learning …

Real‐time diffusion‐perfusion mismatch analysis in acute stroke

M Straka, GW Albers, R Bammer - Journal of Magnetic …, 2010 - Wiley Online Library
Diffusion‐perfusion mismatch can be used to identify acute stroke patients that could benefit
from reperfusion therapies. Early assessment of the mismatch facilitates necessary …

Comparison of perfusion CT software to predict the final infarct volume after thrombectomy

F Austein, C Riedel, T Kerby, J Meyne, A Binder… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Computed tomographic perfusion represents an interesting
physiological imaging modality to select patients for reperfusion therapy in acute ischemic …