Is composition of brain clot retrieved by mechanical thrombectomy associated with stroke aetiology and clinical outcomes in acute ischemic stroke?—a systematic …
J Huang, MC Killingsworth, SMM Bhaskar - Neurology International, 2022 - mdpi.com
Background: Brain clots retrieved following endovascular thrombectomy in acute ischemic
stroke patients may offer unique opportunities to characterise stroke aetiology and aid stroke …
stroke patients may offer unique opportunities to characterise stroke aetiology and aid stroke …
Advancing Stroke Research on Cerebral Thrombi with Omic Technologies
G Costamagna, S Bonato, S Corti… - International Journal of …, 2023 - mdpi.com
Cerebrovascular diseases represent a leading cause of disability, morbidity, and death
worldwide. In the last decade, the advances in endovascular procedures have not only …
worldwide. In the last decade, the advances in endovascular procedures have not only …
Gene expression profiles of ischemic stroke clots retrieved by mechanical thrombectomy are associated with disease etiology
Background Determining stroke etiology is crucial for secondary prevention, but intensive
workups fail to classify~ 30% of strokes that are cryptogenic. Objective To examine the …
workups fail to classify~ 30% of strokes that are cryptogenic. Objective To examine the …
Profiling of circulating gene expression reveals molecular signatures associated with intracranial aneurysm rupture risk
Background Following detection, rupture risk assessment for intracranial aneurysms (IAs) is
critical. Towards molecular prognostics, we hypothesized that circulating blood RNA …
critical. Towards molecular prognostics, we hypothesized that circulating blood RNA …
Swiss vascular biobank: Evaluation of optimal extraction method and admission solution for preserving RNA from human vascular tissue
Proper biobanking is essential for obtaining reliable data, particularly for next-generation
sequencing approaches. Diseased vascular tissues, having extended atherosclerotic …
sequencing approaches. Diseased vascular tissues, having extended atherosclerotic …
Plasma-free blood as a potential alternative to whole blood for transcriptomic analysis
Q Chen, X Guo, H Wang, S Sun, H Jiang, P Zhang… - Phenomics, 2023 - Springer
RNA sequencing (RNAseq) technology has become increasingly important in precision
medicine and clinical diagnostics, and emerged as a powerful tool for identifying protein …
medicine and clinical diagnostics, and emerged as a powerful tool for identifying protein …
New Insights into Cerebral Vessel Disease Landscapes at Single-Cell Resolution: Pathogenetic and Therapeutic Perspectives
M Meneri, S Bonato, D Gagliardi, GP Comi, S Corti - Biomedicines, 2022 - mdpi.com
Cerebrovascular diseases are a leading cause of death and disability globally. The
development of new therapeutic targets for cerebrovascular diseases (eg, ischemic, and …
development of new therapeutic targets for cerebrovascular diseases (eg, ischemic, and …
Multi-omic investigation of retrieved blood clots may identify complex traits associated with ischemic stroke etiology
Multi-Omic Investigation of Retrieved Blood Clots May Identify Complex Traits Associated with
Ischemic Stroke Etiology Multi-Omic Investigation of Retrieved Blood Clots May Identify Complex …
Ischemic Stroke Etiology Multi-Omic Investigation of Retrieved Blood Clots May Identify Complex …
Transcriptome Analysis Identified SPP1+ Monocytes as a Key in Extracellular Matrix Formation in Thrombi
T Kitano, T Sasaki, T Matsui, M Kohara, K Ogawa… - bioRxiv, 2024 - biorxiv.org
Thrombi follow various natural courses. They are known to become harder over time and
may persist long-term; some of them can also undergo early spontaneous dissolution and …
may persist long-term; some of them can also undergo early spontaneous dissolution and …
Plasma-free samples for transcriptomic analysis: a potential alternative to whole blood samples
Q Chen, X Guo, H Wang, S Sun, H Jiang, P Zhang… - bioRxiv, 2023 - biorxiv.org
RNA sequencing (RNAseq) technology has become increasingly important in precision
medicine and clinical diagnostics and emerged as a powerful tool for identifying protein …
medicine and clinical diagnostics and emerged as a powerful tool for identifying protein …