Authors
Tibor Becske, Waleed Brinjikji, Matthew B Potts, David F Kallmes, Maksim Shapiro, Christopher J Moran, Elad I Levy, Cameron G McDougall, István Szikora, Giuseppe Lanzino, Henry H Woo, Demetrius K Lopes, Adnan H Siddiqui, Felipe C Albuquerque, David J Fiorella, Isil Saatci, Saruhan H Cekirge, Aaron L Berez, Daniel J Cher, Zsolt Berentei, Miklós Marosfői, Peter K Nelson
Publication date
2017/1/1
Journal
Neurosurgery
Volume
80
Issue
1
Pages
40-48
Publisher
LWW
Description
BACKGROUND: Early and mid-term safety and efficacy of aneurysm treatment with the Pipeline Embolization Device (PED) has been well demonstrated in prior studies.
OBJECTIVE: To present 5-yr follow-up for patients treated in the Pipeline for Uncoilable or Failed Aneurysms clinical trial.
METHODS: In our prospective, multicenter trial, 109 complex internal carotid artery (ICA) aneurysms in 107 subjects were treated with the PED. Patients were followed per a standardized protocol at 180 d and 1, 3, and 5 yr. Aneurysm occlusion, in-stent stenosis, modified Rankin Scale scores, and complications were recorded.
RESULTS: The primary endpoint of complete aneurysm occlusion at 180 d (73.6%) was previously reported. Aneurysm occlusion for those patients with angiographic follow-up progressively increased over time to 86.8%(79/91), 93.4%(71/76), and 95.2%(60/63) at 1, 3, and 5 yr, respectively. Six aneurysms …
Scholar articles
T Becske, W Brinjikji, MB Potts, DF Kallmes, M Shapiro… - Neurosurgery, 2017