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How mammals acquire and distribute iron needed for oxygen-based metabolism

PLoS Biol. 2003 Dec;1(3):E79. doi: 10.1371/journal.pbio.0000079. Epub 2003 Dec 22.

Abstract

All organisms require iron for respiration and oxygen transport, thus elaborate systems for uptake and distribution of iron are found throughout the kingdoms of life

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Iron / metabolism*
  • Mammals
  • Models, Biological
  • Oxygen / metabolism*
  • Receptors, Transferrin / genetics
  • Receptors, Transferrin / metabolism
  • Receptors, Transferrin / physiology*
  • Transferrin / metabolism

Substances

  • Receptors, Transferrin
  • Transferrin
  • Iron
  • Oxygen