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Behavioral Interventions to Prevent or Delay Dementia: Protocol for a Randomized Comparative Effectiveness Study

Behavioral Interventions to Prevent or Delay Dementia: Protocol for a Randomized Comparative Effectiveness Study

The majority of people with dementia (75%) live at home where they receive 83% of their care from informal caregivers—unpaid individuals such as family members, friends, and neighbors [1] . These caregivers provide valuable services, often at great economic, health, and psychological cost to themselves. Hurd et al [4] estimate the average annual cost of dementia care to be US $56,290, of which more than half is in unpaid care.

Glenn Eric Smith, Melanie Chandler, Dona EC Locke, Julie Fields, Vaishali Phatak, Julia Crook, Sherrie Hanna, Angela Lunde, Miranda Morris, Michelle Graff-Radford, Christine A Hughes, Susan Lepore, Andrea Cuc, Maria Caselli, Duane Hurst, Jennifer Wethe, Andrea Francone, Jeanne Eilertsen, Pauline Lucas, Charlene Hoffman Snyder, LeeAnn Kuang, Marigrace Becker, Pamela Dean, Nancy Diehl, Marvin Lofquist, Shirley Vanderhook, Diana Myles, Denise Cochran

JMIR Res Protoc 2017;6(11):e223


The Association of Health Literacy and Electronic Health Literacy With Self-Efficacy, Coping, and Caregiving Perceptions Among Carers of People With Dementia: Research Protocol for a Descriptive Correlational Study

The Association of Health Literacy and Electronic Health Literacy With Self-Efficacy, Coping, and Caregiving Perceptions Among Carers of People With Dementia: Research Protocol for a Descriptive Correlational Study

The main research questions are RQ1a: What is the level of health literacy and e Health literacy of dementia patients’ primary carers? RQ1b: What is the level of health literacy and e Health literacy of dementia patients’ secondary carers? RQ2: Is there a difference between health literacy and e Health literacy level of dementia patients’ primary and secondary carers, given the generation gap?

Areti Efthymiou, Nicos Middleton, Andreas Charalambous, Evridiki Papastavrou

JMIR Res Protoc 2017;6(11):e221


Validation of a Computerized, Game-based Assessment Strategy to Measure Training Effects on Motor-Cognitive Functions in People With Dementia

Validation of a Computerized, Game-based Assessment Strategy to Measure Training Effects on Motor-Cognitive Functions in People With Dementia

Recent studies could show that applications such as tablet mobile devices with integrated memory training apps can be used even by people with early stage of dementia [1,2]. Some reviews reported that exergames that combine physical activity with digital gaming have also been found wide application in healthy [3], disabled older adults [4], and in people with cognitive impairment or dementia [5-7].

Stefanie Sandra Wiloth, Nele Lemke, Christian Werner, Klaus Hauer

JMIR Serious Games 2016;4(2):e12


Association of Rest-Activity Rhythm and Risk of Developing Dementia or Mild Cognitive Impairment in the Middle-Aged and Older Population: Prospective Cohort Study

Association of Rest-Activity Rhythm and Risk of Developing Dementia or Mild Cognitive Impairment in the Middle-Aged and Older Population: Prospective Cohort Study

Dementia represents a major public health concern with profound social, economic, and health care implications, and it is a leading cause of disability and dependency among the older adult population. It is estimated that over 55 million individuals worldwide are affected by dementia [1]. As the global population ages, understanding the etiology and potential risk factors associated with dementia has become a critical area of research.

Shahab Haghayegh, Chenlu Gao, Elizabeth Sugg, Xi Zheng, Hui-Wen Yang, Richa Saxena, Martin K Rutter, Michael Weedon, Agustin Ibanez, David A Bennett, Peng Li, Lei Gao, Kun Hu

JMIR Public Health Surveill 2024;10:e55211


Development and Evaluation of a Clinician-Vetted Dementia Caregiver Resources Website: Mixed Methods Approach

Development and Evaluation of a Clinician-Vetted Dementia Caregiver Resources Website: Mixed Methods Approach

The proportion of the world population that is aged over 60 years old is projected to almost double between 2015 and 2050 [1], and with it, the prevalence of dementia and the number of families caring for people with dementia will also increase. About 11 million Americans (70% female) currently provide 18 billion hours of unpaid dementia care per year [2], many without formal dementia education or support.

Jaye E McLaren, Dat Hoang-Gia, Eugenia Dorisca, Stephanie Hartz, Stuti Dang, Lauren Moo

JMIR Form Res 2024;8:e54168


Digital Storytelling Intervention for Enhancing the Social Participation of People With Mild Cognitive Impairment: Co-Design and Usability Study

Digital Storytelling Intervention for Enhancing the Social Participation of People With Mild Cognitive Impairment: Co-Design and Usability Study

Social participation has proven efficacious in decelerating the progression of dementia from mild cognitive impairment (MCI) [1], particularly in low- and middle-income countries [2]. To enhance social participation among older adults with MCI, researchers are engaged in reducing the obstructions to social participation [3] and creating and customizing a variety of constructive social activities [4].

Di Zhu, Abdullah Al Mahmud, Wei Liu

JMIR Aging 2024;7:e54138


Cognitive Dysfunction and Affective Mood Disorder Screening in Patients With Chronic Inflammatory Bowel Disease: Protocol for a Prospective Case-Control Study

Cognitive Dysfunction and Affective Mood Disorder Screening in Patients With Chronic Inflammatory Bowel Disease: Protocol for a Prospective Case-Control Study

MCI is often considered a transitional stage between normal aging and more severe forms of cognitive decline, such as dementia. MCI is most commonly characterized by memory problems, such as difficulty in recalling names and recent events, but it can also involve problems with other cognitive abilities, such as language, decision-making, and attention. The impairment of daily activities is a key criterion to diagnosing dementia and the difference between MCI and dementia [4].

Oliviu Florentiu Sarb, Vitalie Vacaras, Adriana Sarb, Maria Iacobescu, Alina-Ioana Tantau

JMIR Res Protoc 2023;12:e50546


Mindfulness-Based App to Reduce Stress in Caregivers of Persons With Alzheimer Disease and Related Dementias: Protocol for a Single-Blind Feasibility Proof-of-Concept Randomized Controlled Trial

Mindfulness-Based App to Reduce Stress in Caregivers of Persons With Alzheimer Disease and Related Dementias: Protocol for a Single-Blind Feasibility Proof-of-Concept Randomized Controlled Trial

firstnamelastname ####@gmail.com), (2) spelling mistakes and grammatical errors, (3) incorrect or inconsistent survey responses (eg, one participant wrote they heard about this study on Craigslist), (4) providing out-of-service or Google Voice (Google LLC) numbers (the use of Google Voice numbers has been cited as a commonality among many imposter participants [51]), (5) poor sound quality during phone calls, and (6) exaggerated or illogical statements during phone calls (eg, stating, “I take my father with advanced dementia

Emily C Woodworth, Ellie A Briskin, Evan Plys, Eric Macklin, Raquel G Tatar, Jennifer Huberty, Ana-Maria Vranceanu

JMIR Res Protoc 2023;12:e50108


Performance Differences of a Touch-Based Serial Reaction Time Task in Healthy Older Participants and Older Participants With Cognitive Impairment on a Tablet: Experimental Study

Performance Differences of a Touch-Based Serial Reaction Time Task in Healthy Older Participants and Older Participants With Cognitive Impairment on a Tablet: Experimental Study

In addition, a large number of dementia diseases may be mixed pictures of different subtypes of dementia [55,56]. This phenomenon may further contribute to the divergent findings. In a review and meta-analysis, de Wit et al [8] discuss the difficulty of participants with AD in understanding and remembering the test instructions of SRTT paradigms. Most studies found differences in response accuracy and reaction times (with participants with Co I being slower than HC participants).

Christian Mychajliw, Heiko Holz, Nathalie Minuth, Kristina Dawidowsky, Gerhard Wilhelm Eschweiler, Florian Gerhard Metzger, Franz Wortha

JMIR Aging 2024;7:e48265