Omeprazole: Difference between revisions

Omeprazole contains a tricoordinated sulfonylsulfinyl sulfur in a pyramidal structure and therefore can exist as either the (''S'')- or (''R'')-[[enantiomer]]s. Omeprazole is a [[racemate]], an equal mixture of the two. In the acidic conditions of the [[canaliculus (parietal cell)|canaliculi]] of [[parietal cells]], both enantiomers are converted to [[achiral]] products ([[sulfenic acid]] and [[sulfenamide]] configurations) which react with a [[cysteine]] group in [[Hydrogen potassium ATPase|H⁺/K⁺ ATPase]], thereby inhibiting the ability of the parietal cells to produce [[gastric acid]].{{citation needed|date=March 2016}}