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From the posterior wall of the [[saccule]] a canal, the [[endolymphatic duct]], is given off; this duct is joined by the [[utriculosaccular duct]], and then passes along the [[vestibular aqueduct]] and ends in a blind pouch, the '''endolymphatic sac''', on the posterior surface of the [[Petrous portion of the temporal bone|petrous portion]] of the [[temporal bone]], where it is in contact with the [[dura mater]]. Studies suggest that the endolymphatic duct and endolymphatic sac perform both absorptive and [[secretory]],<ref>Schuknecht HF. Pathology of the Ear. Philadelphia, Pa: Lea & Febiger; 1993:45–47, 50–51, 62, 64, 101</ref><ref>{{Cite journal |last=Wackym PA,|first=P. A. |last2=Friberg |first2=U,. |last3=Bagger-Sjo¨ba¨ckSjöbäck |first3=D,. |last4=Linthicum FH|first4=F. Jr,H. |last5=Friedmann |first5=I,. |last6=Rask-Andersen |first6=H. |date=1987-08 |title=Human endolymphatic sac: possible mechanisms of pressure regulation |url=https://pubmed.ncbi.nlm.nih.gov/3655528/ J|journal=The LaryngolJournal Otolof 1987;Laryngology and Otology |volume=101: |issue=8 |pages=768–779 |doi=10.1017/s0022215100102713 |issn=0022-2151 |pmid=3655528}}</ref><ref>{{Cite journal |last=Yeo SW,|first=S. W. |last2=Gottschlich |first2=S,. |last3=Harris JP,|first3=J. P. |last4=Keithley EM|first4=E. M. |date=1995-06 |title=Antigen diffusion from the perilymphatic space of the cochlea |url=https://pubmed.ncbi.nlm.nih.gov/7769947/ |journal=The Laryngoscope 1995;|volume=105 |issue=6 |pages=623–628 |doi=10.1288/00005537-199506000-00012 |issn=0023-852X |pmid=7769947}}</ref><ref>{{Cite journal |last=Rask-Andersen |first=H. |last2=Danckwardt-Lillieström |first2=N. |last3=Linthicum |first3=F. H. |last4=House |first4=W. F. |date=1991-02 |title=Ultrastructural evidence of a merocrine secretion in the human endolymphatic sac |url=https://pubmed.ncbi.nlm.nih.gov/1992902/ |journal=The Annals of Otology, Rhinology, and Laryngology |volume=100 |issue=2 |pages=148–156 |doi=10.1177/000348949110000211 |issn=0003-4894 |pmid=1992902}}</ref> as well as phagocytic<ref>{{Cite journal |last=Fukazawa |first=K. |last2=Sakagami |first2=M. |last3=Matsunaga |first3=T. |last4=Fujita |first4=H. |date=1991-07 |title=Endocytotic activity of the free floating cells and epithelial cells in the endolymphatic sac: an electron microscopic study |url=https://pubmed.ncbi.nlm.nih.gov/1867416/ |journal=The Anatomical Record |volume=230 |issue=3 |pages=425–433 |doi=10.1002/ar.1092300315 |issn=0003-276X |pmid=1867416}}</ref> and immunodefensive, functions.<ref>{{Cite journal |last=Wackym |first=P. A. |last2=Friberg |first2=U. |last3=Linthicum |first3=F. H. |last4=Bagger-Sjöbäck |first4=D. |last5=Bui |first5=H. T. |last6=Hofman |first6=F. |last7=Rask-Andersen |first7=H. |date=1987 |title=Human endolymphatic sac: morphologic evidence of immunologic function |url=https://pubmed.ncbi.nlm.nih.gov/3300505/ |journal=The Annals of Otology, Rhinology, and Laryngology |volume=96 |issue=3 Pt 1 |pages=276–281 |doi=10.1177/000348948709600308 |issn=0003-4894 |pmid=3300505}}</ref>
105:623–628</ref><ref>Rask-Andersen H, Danckwardt-Lilliestrom N, Linthicum FH, House WF. Ultrastructural evidence of a merocrine secretion in the human endolymphatic sac. Ann Otol Rhinol Laryngol 1991; 100:148–156</ref> as well as phagocytic<ref>Fukuzawa K, Sakagami M, Matsunaga T, Fujita H. Endocytotic activity of the free floating cells and epithelial cells in the endolymphatic sac: an electron microscopic study. Anat Rec 1991; 230:425–433</ref> and immunodefensive, functions.<ref>Wackym PA, Friberg U, Linthicum FH Jr, et al. Human endolymphatic sac: morphologic evidence of immunologic function. Ann Otol Rhinol Laryngol 1987;96:276–282</ref>
[[Endolymphatic sac tumor|Neoplasms of the endolymphatic sac]] are very rare tumors.
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