Yttrium (90Y) tacatuzumab tetraxetan: Difference between revisions
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{{Short description|Monoclonal antibody}} |
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{{DISPLAYTITLE:Yttrium (<sup>90</sup>Y) tacatuzumab tetraxetan}} |
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| image = Y-90 tacatuzumab tetraxetan structure.svg |
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| drug_name = Yttrium (<sup>90</sup>Y) tacatuzumab tetraxetan |
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<!-- Monoclonal antibody data --> |
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| type = mab |
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| mab_type = mab |
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| source = zu/o |
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| target = [[α-fetoprotein]] |
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<!-- Chemical data --> |
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| chemical_formula = C<sub>6470</sub>H<sub>9971</sub>N<sub>1712</sub>O<sub>2007</sub>S<sub>42</sub><sup>90</sup>Y |
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| molecular_weight_comment = kg/mol |
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'''Yttrium (<sup>90</sup>Y) tacatuzumab tetraxetan''' is an investigational [[humanized monoclonal antibody]] intended for the treatment of cancer.<ref>{{cite web|url=http://www.ama-assn.org/ama1/pub/upload/mm/365/yttrium_90_tacatuz.doc|url-status=dead|archive-url=https://web.archive.org/web/20040911162110/http://www.ama-assn.org/ama1/pub/upload/mm/365/yttrium_90_tacatuz.doc|date=4 September 2004 |title=Statement On A Nonproprietary Name Adopted By The USAN Council|archive-date=2004-09-11 }}</ref> The antibody itself, tacatuzumab, is conjugated with [[tetraxetan]], a [[chelator]] for [[yttrium-90]],<ref>[https://web.archive.org/web/20110705093023/http://apps.who.int/medicinedocs/documents/s14179e/s14179e.pdf WHO Drug Information]</ref> a [[radioisotope]] which destroys the tumour cells. |
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'''Tacatuzumab tetraxetan''' is a [[Humanize|humanized]] [[monoclonal antibody]] and which it's used to treat cancer. Tacatuzumab has a [[chelator]], [[tetraxetan]]. It has a [[radioisotope]], [[yttrium]]-99Y. |
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==References== |
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{{reflist}} |
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{{Monoclonals for tumors}} |
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{{DEFAULTSORT:Yttrium Tacatuzumab Tetraxetan}} |
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[[Category:Antibody-drug conjugates]] |
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[[Category:Radiopharmaceuticals]] |
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[[Category:Experimental cancer drugs]] |
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[[Category:DOTA (chelator) derivatives]] |
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{{humanizedmonoclonals}} |
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{{monoclonal-antibody-stub}} |
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{{nuclear-med-stub}} |
Latest revision as of 06:30, 31 December 2023
Monoclonal antibody | |
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Type | Whole antibody |
Source | Humanized (from mouse) |
Target | α-fetoprotein |
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Chemical and physical data | |
Formula | C6470H9971N1712O2007S4290Y |
Molar mass | 145 kg/mol |
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Yttrium (90Y) tacatuzumab tetraxetan is an investigational humanized monoclonal antibody intended for the treatment of cancer.[1] The antibody itself, tacatuzumab, is conjugated with tetraxetan, a chelator for yttrium-90,[2] a radioisotope which destroys the tumour cells.
References[edit]
- ^ "Statement On A Nonproprietary Name Adopted By The USAN Council". 4 September 2004. Archived from the original on 2004-09-11.
- ^ WHO Drug Information