Circuitry-based neuroimaging analyses can enhance our understanding of abnormal brain functioning in patients with major depressive disorder and other psychiatric conditions — but their utility for guiding treatment selection is less certain.
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References
Tozzi, L. et al. Nat. Med. https://doi.org/10.1038/s41591-024-03057-9 (2024).
Goldstein-Piekarski, A. N. et al. Biol. Psychiatry 91, 561–571 (2022).
Mayberg, H. S. & Dunlop, B. W. World Psychiatry 23, 265–267 (2023).
Phillips, M. L. et al. Am. J. Psychiatry 172, 124–138 (2015).
Schatzberg, A. F. Am. J. Psychiatry 178, 372–374 (2021).
Figee, M. & Mayberg, H. Nat. Med. 27, 196–197 (2021).
Krystal, A. D. et al. Nat. Med. 26, 760–768 (2020).
McIntyre, R. S. et al. J. Clin. Psychopharmacol. 37, 412–418 (2017).
Fennema, D. et al. Biol. Psychiatry Glob. Open Sci. 4, 100308 (2024).
Dunlop, B. W. et al. Am. J. Psychiatry 174, 533–545 (2017).
Dunlop, B. W. et al. Am. J. Psychiatry 180, 218–229 (2023).
McGrath, C. L. et al. Biol. Psychiatry 76, 527–535 (2014).
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B.W.D. has received research support from Boehringer-Ingelheim, Compass Pathways, Intra-Cellular Therapies, NIMH and Usona, and has received consulting fees from Biohaven, Cerebral Therapeutics, Department of Defense, Myriad Neuroscience and Otsuka. H.S.M. receives research support from NIMH, NINDS BRAIN, Wellcome LEAP, Hope for Depression Research Foundation, and consulting and IP licensing fees from Abbott Neuromodulation.
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Dunlop, B.W., Mayberg, H.S. The capacity of brain circuits to enhance psychiatry. Nat Med (2024). https://doi.org/10.1038/s41591-024-03090-8
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DOI: https://doi.org/10.1038/s41591-024-03090-8