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2013, International Journal of Cardiology
Indian Journal of Thoracic and Cardiovascular Surgery
Effects of single dose methylprednisolone on patient recovery after cardiopulmonary bypass2012 •
European Journal of Cardio-thoracic Surgery
Is incidence of postoperative vasoplegic syndrome different between off-pump and on-pump coronary artery bypass grafting surgery2008 •
PubMed
Role of methylprednisolone in the prevention of postpericardiotomy syndrome after cardiac surgery2016 •
Objective: Postpericardiotomy syndrome (PPS) occurs in 10-40% of patients after cardiac operations. Pericardial effusions and tamponade occurring > 7 days after surgery are usually related to PPS and remain an important cause of cardiac surgery-related morbidity and mortality; therefore, preventing PPS is important. Colchicine affords safe and efficacious protection against PPS and related complications. However, the roles of corticosteroids and nonsteroidal anti-inflammatory drugs in PPS prevention remains unclear. This study aimed to determine whether the intraoperative use of single-dose methylprednisolone can effectively prevent PPS. Patients and methods: This retrospective study included 100 patients undergoing elective coronary artery bypass grafting (CABG) who received a single intraoperative dose of 1 mg/kg methylprednisolone. A further 100 patients undergoing CABG, who were not given methylprednisolone, comprised the control group. The presence and severity of pericardial effusion was determined by echocardiography, with chest X-ray used to assess pleural effusion. Results: PPS occurrence and pericardial effusion occurrence were significantly lower in patients who received methylprednisolone (p = 0.02 and p = 0.007 respectively). Although the differences were not statistically significant, pericardial and pleural effusions were more severe in the control group than in the methylprednisolone group. Logistic regression analysis demonstrated that methylprednisolone administration was independently associated with prevention of PPS (OR 0.8, 95% CI 0.25-0.91, p < 0.026). Conclusions: Intraoperative, single-dose methylprednisolone may confer protection against PPS in patients undergoing CABG.
2014 •
Basic Research in Cardiology
Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation?2011 •
Brazilian Journal of Cardiovascular Surgery
Comparison of the operative and postoperative effects of del Nido and blood cardioplegia solutions in cardiopulmonary bypass surgery2020 •
2002 •
Background: The reported incidence of AF after CABG surgery varies from 20 to 40%, with the arrhythmia usually occurring between second and fourth postoperative days. Postoperative AF after CABG was associated with greater in-hospital mortality and worse survival at long-term follow-up. Therefore, intensive attention has focused on the prevention of AF in high-risk patients. Many perioperative factors have been suggested to increase the incidence of postoperative AF after conventional CABG. In this study we are trying to examine some of these risk factors as predictors for Post-operative AF in our patients. In this study, our aim was to identify the perioperative predictors of AF in our patients who underwent Coronary Artery Bypass Grafting. Methods: Our Patients were divided into two groups; Group A included patients who did not develop PO AF (168 patients) and Group B patients who developed PO AF (84 patients). Perioperative Data, including gender, age, demographic variables and postoperative morbidity and mortality were extracted from the medical records. Results: This retrospective cohort study was conducted on 252 consecutive adult patients underwent CABG, in King Faisal Specialist Hospital and Research Center in Jeddah, Saudi Arabia. The mean age for patients with PO AF was 65 years (P = .0001). Eight-three patients (49.4%) were diabetics in group A and 56 patients (66.7%) in group B (P = .0001). Patients who developed POAF had a lower ejection fraction (44.8 ± 5.7%) (P = .0001), diastolic dysfunction (P = .0001), Larger Left atrial volume (P = .0001). Bleeding requiring reopening for exploration and Postoperative shock were identified as significant predictors for POAF. Multivariate logistic regression (odds ratio, ±95% CI, P value) was performed to identify the effect of age, preoperative heart rate, ejection fraction, postoperative bleeding, Shock, ventilator time, Sensitivity was 89.5%, specificity was 94.6%, positive predictive value was 89.5%, and negative predictive value was 94.6%.
Immunology Letters
Skin homing receptor expression in lymphocytes from subjects with allergic drugs reactions1997 •
Journal of Mental Health Research in Intellectual Disabilities
A Systematic Review of the Rates of Depression in Children and Adults With High-Functioning Autism Spectrum Disorder2017 •
IEEE Transactions on Audio, Speech, and Language Processing
Transforming Perceived Vocal Effort and Breathiness Using Adaptive Pre-Emphasis Linear Prediction2008 •
Child & Family Social Work
What Works in Residential Child Care: A Review of Research Evidence and the Practical Considerations2008 •
Alzheimer's & Dementia
Neuroprotective effects of cerebrolysin in a Picks-like model of tauopathy2012 •
Développement durable et territoires
Le développement durable face au territoire : éléments pour une recherche pluridisciplinaire2002 •