Stroll a quarter of a mile from the Art Noveau–styled ICON Hotel & Lounge (from $120) to the National Museum and Wenceslas Square, Prague’s elegant shopping boulevard. Admire the work of Czech fashion photographer Kámen in the hotel’s rotating gallery, on display through November.
Lounge on Cubist-inspired furniture at the Augustine (from $270), a luxury hotel that shares its serene grounds with a thirteenth-century Augustinian monastery (several monks still reside within). Sip a locally brewed St. Thomas Beer at the Brewery Bar, a cavelike space in the hotel cellar.
Request room 602 for the best views of Prague Castle from Mosaic House (from $60), an ecofriendly, solar-powered boutique hotel. Belushi’s, the ground-floor bar and garden terrace, draws guests and raucous locals until 2 a.m. for it $20 mojito pitchers.